机械通气在救治危重肺源性心脏病呼吸衰竭患者中的疗效观察

Clinical efficacy of mechanical ventilation in treatment of critical Patients with cor pulmonale with respiratory failure

目的:探讨将机械通气应用于危重肺源性心脏病呼吸衰竭患者的救治中的临床疗效及应用价值。方法:回顾性分析近3年我院收治的危重肺源性心脏病呼吸衰竭患者143例,其中有53例患者采用诊断肺源性心脏病的药物治疗(对照组),90例患者在对照组治疗的基础上采用机械通气治疗(通气组),对比2组的治疗效果。结果:治疗2周后,通气组患者的PaO_2、PH显著高于对照组P<0.01;而HR、PaCO_2及住院天数显著较低,P<0.01。对照组和通气组患者在治疗1天后肺功能(FEV1)改善情况无统计学差异,P>0.05;通气组患者在治疗3天、7天机2周后肺功能(FEV1)改善情况显著优于对照组,P<0.05。结论:对重症肺源性心脏病呼吸衰竭患者采用机械通气救治是有效的较安全的。

Objective：To investigate the mechanical ventilation used in critically ill patients with respiratory failure,pulmonary heart disease in clinical efficacy of treatment and value.Methods：A retrospective analysis of recently years in our hospital with respiratory failure in critically ill patients with pulmonary heart disease,143 cases of which 53 patients were treated with the drug for the treatment of pulmonary heart disease（control group）,90patients in the control group treatment based on the use of mechanical ventilation（ventilation group）,compared two groups of treatment.Results：After 2weeks of treatment,ventilation group of patients with PaO_2,PH were significantly higher,p0.01;and HR,PaO_2,and hospital;stay were significantly lower,P0.01.Ventilation group and the control group after 1 day in the treatment of patients with lung function（FEV1） to improve the situation was no significant difference,P0.05;ventilation of patients in treatment for 3days,7days and 2 weeks after the lung function（FEV1 ） was significantly superior improvement in the control group,P0.05.Conclusion：Severe respiratory failure in patients with pulmonary heart disease treatment with mechanical ventilation might be effective safer.