宁波市社区人群痛风与高尿酸血症的现况研究

A Cross - sectional Study on Gout and Hyperuricemia in Community Population

目的了解宁波市社区人群痛风与高尿酸血症的流行情况,分析相关致病因素。方法采用分层随机抽样调查方法,共抽取社区人群1754人,检测血尿酸均值,并采用问卷调查,对可疑患者作诊断性检查。结果高尿酸血症检出率男性为12.54%;女性为9.64%。发现痛风病患者5例,患病率为0.29%。血尿酸均值男性高于女性,脑力劳动者高于体力劳动者,沿海地区高于内陆地区,差异均有统计学意义(P<0.01)。结论宁波地区居民高尿酸血症检出率相对较高,食用高嘌呤海产品可能是当地高尿酸血症重要的危险因素。

Objective To Understand the epidemiological situation of gout and hyperuricemia in the community population of Ningbo, and its related factors. Methods This investigation was carried out in community population with the method of random stratified sampling. We recruited 1754 participants totally to test the mean value of blood uric acid, and a questionnaire was taken to survey the related factors, then the suspected patients were diagnosed. Results The detect rate of hyperuricemia was 12.54% in men and 9.64% in women, respectively. 5 cases of gout patients were found in this survey; the prevalence rate was 0.29%. The mean value of blood uric acid in men was higher than in women, in mental labors was higher than in manual workers, and in coastal areas was higher than in inland. All these differences were statistically significant （ P 〈 0. 05 ）. Conclusion The prevalence of hyperuricemia and gout of residents in the Ningbo area was on a much higher level, and consumption of high purine seafood may be a related risk factor for hyperuricemia.