杭州市HIV阳性男男性行为人群梅毒感染状况及危险因素分析

An Analysis of Infection Status of Syphilis and Its Risk Factors among HIV Positive MSM in Hangzhou

目的调查杭州市HIV阳性男男性行为(MSM)人群梅毒感染状况,探索可能的危险因素。方法对杭州市HIV阳性男男性行为人群进行问卷调查,并采集血样进行梅毒和CD4细胞检测。计算梅毒的感染率和可信区间,使用Logistic回归分析梅毒感染的危险因素。结果在调查的460人中,梅毒阳性138人,感染率为30.00%,95%可信区间为25.81%～34.19%;年龄(OR=1.58,95%CI:1.23～2.02)、性病史(OR=2.41,95%CI:1.52～3.83)和同性性伴数(OR=2.05,95%CI:1.28～3.28)差异有统计学意义(P<0.05),是感染梅毒的危险因素。结论杭州市HIV阳性男男性行为人群中梅毒的感染率较高,在预防控制HIV的同时,应采取措施积极预防梅毒流行。

Objective To understand the infection status of syphilis and its risk factors among HIV positive MSM （ Men who have sex with men） in Hangzhou. Methods A cross - sectional investigation was performed among HIV positive MSM. After the face - to - face： questionnaire interview, 5 - 10 ml blood sample was collected for the syphilis detection and CD4 cells count test. The risk factors of syphilis infection were analyzed with logistic regression. Results 460 HIV positive MSM were recruited in this survey, in which 138 were co - infected with syphilis. The prevalence of syphilis was 30% （95 % CI： 25.81% - 34. 19 % ）. Age （ OR = 1.58 ; 95 % CI： 1.23 - 2. 02） , the STDs history （ OR =2.41 ; 95% C/; 1.52 -3.83） and the number of homosexual paxtuers （ OR =2.05 ; 95 ;CI;, 1.28 -3.28） were the risk factors for syphilis infection. Conclusion The syphilis prevalence rate among HIV positive MSM is high in Hangzhou, suggesting some effective measures should be taken to prevent the infection of syphilis when preventing and controlling the HIV infection.