中药保留灌肠联合艾灸治疗放射性肠炎63例临床观察

Observation of retention enema of traditional Chinese medicine combined with moxibustion treatment on radiation enteritis

目的观察中药保留灌肠联合艾灸治疗放射性肠炎(RE)的临床疗效。方法将123例RE患者随机分为2组。治疗组63例予中药保留灌肠联合艾灸治疗,对照组60例予常规西药治疗。2组治疗1个月后观察疗效,比较治疗前后中医症状积分变化。结果治疗组总有效率92.1%,对照组总有效率76.7%,2组总有效率比较差异有统计学意义(P<0.05),治疗组疗效优于对照组。治疗组治疗后黏液脓血便、腹泻、腹痛、里急后重积分均低于本组治疗前及对照组治疗后(P<0.01);对照组治疗后腹泻、腹痛积分均低于本组治疗前(P<0.01,P<0.05)。结论中药保留灌肠联合艾灸治疗RE,疗效较好,安全、副作用少,患者依从性较好,为RE的有效治疗方案之一。

Objective To observe the effect of retention enema of traditional Chinese medicine combined with moxibustion treatment on radiation enteritis. Methods 123 patients with radiation enteritis were randomly divid- ed into two groups. 60 cases of the control group received conventional western medicine. And 63 cases of the treat- ment group received retention enema of traditional Chinese medicine combined with moxibustion treatment. Improve- ment of clinical symptoms in the two groups was compared before and after treatment. Results The total effective rate in the treatment group and the control group was 92. 1% and 76.7% , and difference of efficacy between two groups was statistically significant （ P 〈 0.05 ）. After treatment, scores of mucus bloody purulent stool, diarrhea, abdom- inal pain and tenesmus were lower than those before treatment in treatment group and after treatment in control group （ P 〈 0.01 ）. Conclusion Retention enema of traditional Chinese medicine combined with moxibustion treatment has a better efficacy, safety, fewer side effects and better patient compliance, it is one of the effective treatment programs of radiation enteritis.