西安地区妇女和儿童血清中检出人细小病毒B_(19)抗体

Serum antibodies to human Parvovirus B_(19) detected from women and children in Xi'an region

作者用人细小病毒B_(19)蛋白及其单克隆抗体,建立ELISA抗γ捕捉法,检测318名西安地区正常育龄妇女及儿童的血清特异性IgG,结果阳性率分别为29.2％(42/144)和9.0％(16/174),总阳性率为18.2％。其阳性率有随年龄增长而增高的趋势。本文首次在我国证明有此种可致人类多种疾病的小DNA病毒感染。

: Human Parvovirus B 19 (HPV B 19) protein and anti - B19 McAb were used in ELISA for measurement of antibody (IgG) in human sera to HPV 819. 318 serum samples from healthy women (22-38 years old) and children in Xi'an region were obtained and screened by ELISA. Positivily rates of HPV B 19 antibody IgG were 29.2% ( 42/144) in the women group, 9.0% (16/174) in the children group and 18.2% (58/318) in whole samples. And the positivity rate in the children tended to increasing with the age.The above findings demonstrate thatHPV B19 infection exists in Shaanxi, China.