血管紧张素转换酶测定对肺部疾病的诊断意义

Significance of serum angiolensin converting enzyme activity in diagnosis of pulmonary diseases

作者报告正常人113例的血清血管紧张素转换酶(SACF)的活性水平,并与胸腔内结节病11例、肺结核38例和肺癌31例测定结果进行比较,SACE活性正常值为535.94±82.35 nmol s,无性别及年龄差异.胸腔内结节病SACE活性显著高于正常人(864.84±132.03nmol/s P<0.01),活动性者明显高于非活动性者(995.53±133.86vs 585.12±68.51nmol/s P<0.01).肺结核38例SACT与正常人相近(558.45±89.18nmol/sP>0.05),肺癌31例SACE活性低于正常(474.43±127.19nmol s P<0.05),差异显著.SACE活性测定有助于对结节病的诊断和病情观察.对其它肺部疾病有一定鉴别诊断意义.

Serum angiotcmui convening cnzymciSACT ) activity of 113 normal subjects was detected ; its result was compared with the activities from 1 i cases of pulmonary sarcoidosis , 38 cases of pulmonary tuberculosis as well as 31 cases of pulmonary carcinoma . The normal level of SACE was 535.94 ± 82.35 nmol, s . There were no differences between sexes or agx .The levels of SACF. in sarcoidosis were significant higher than that of normal subjects ( 864.84 ± 13203 nmol/s , P<0.01 ), while the level of the cases in active stage was higher than that in resting stag: (995.53 ± 133.86 vs 585.12 ± 68.51 nmol s , P<0.01 ). The mean level of SACE from 38 cases of pulmonary tuberculosis was only slightly higher (558.45 ± 89.18 nmol s , P>0.05 ), but it was much higher in the cases of hematogsnous pulmonary tuberculosis . The SACF. level in 31 cases of pulmonary carcinoma was significant lower (474.43 ± 127.19 nmol/s ,P<0.05 ). In short ,the detection of scrum SACF, activity is helpful in the diagnosis of pulmonary sarcoidosis and in differential diagnosis for other pulmonary diseases .