摘要
Based on the unique properties, nanostructured ZnO could provide a stable immobilization for biomolecules retaining their biological activity. It has been recently developed as a nice candidate for the construction of biosensors with enhanced analytical performance. In this paper, we reviewed the progress in adapting nanostructured ZnO for several predominantly in biosensing applications based on enzymic reaction, immunoreaction, and molecular compitation. We also described several important considerations when working with nanostructured ZnO mainly centered on the fabrications of ZnO and appropriate strategies for biosensor construction (e.g. modified electrodes and multilayered immobilization).
Based on the unique properties, nanostructured ZnO could provide a stable immobilization for biomolecules retaining their bio- logical activity. It has been recently developed as a nice candidate for the construction of biosensors with enhanced analytical performance. In this paper, we reviewed the progress in adapting nanostructured ZnO for several predominantly in biosensing applications based on enzymic reaction, irnmunoreaction, and molecular compitation. We also described several important con- siderations when working with nanostructured ZnO mainly centered on the fabrications of ZnO and appropriate strategies for biosensor construction （e.g. modified electrodes and multilayered immobilization）.
基金
supported by the National Natural Science Foundation of China (60725413 and 60976002)
the National Basic Research Program of China (2011CB302004)
the Ministry of Education (309015)
