鼻部疾病手术前后鼻腔功能的变化

Clinical significance of nasal function examination in diagnosis and treatment of nasal diseases-combined asthma

目的探讨合并鼻部疾病的哮喘患者手术治疗前后效果的评估及鼻腔功能检查在其临床诊疗中的意义。方法通过应用鼻腔功能检查联合改良哮喘控制问卷(ACQ6)对经手术治疗的合并鼻部疾病的哮喘患者(按合并疾病分为鼻中隔组、鼻息肉组、鼻窦炎组)的手术疗效、鼻腔通气功能改善及哮喘症状恢复情况进行评估。结果鼻腔功能检查结果显示所有患者手术前后鼻腔功能检查结果的变化具有统计学意义(P<0.05);鼻中隔组分别与鼻息肉、鼻窦炎组比较,鼻腔功能检查显示前后差异具有统计学意义(P<0.05);鼻息肉与鼻窦炎组比较差异无统计学意义(P>0.05);ACQ6统计结果显示各组手术前后得分比较具有统计学意义(P<0.05),即手术后哮喘症状明显改善,而各组间得分比较差异无统计学意义(P>0.05)。结论合并鼻部疾病的哮喘患者通过鼻部疾病的手术治疗后症状明显改善;鼻腔功能检查及ACQ6的联合使用可为合并鼻部疾病的哮喘患者的防治提供新的临床诊疗思路。

Objective To evaluate the surgical effect for nasal diseases-combined asthma, and to discuss the significance of nasal function examination in the diagnosis and treatment. Methods According to the combined diseases, the asthma patients were divided into nasal septum group, nasal polyps group, and sinusitis group. The surgical effect, improvement of nasal ventilation function and relief of asthma were evaluated and compared across groups via nasal function examination combined with the improved asthma control questionnaire （ ACQ6 ）. Results The nasal function examination showed significant postoperative changes in all groups. The differences of nasal function change between the nasal septum group and nasal polyps group, sinusitis group were statistically significant （P 〈 0.05 ） , while that between the nasal polyps group and the sinusitis group was insignificant （ P 〉 0.05 ）. Statistical results of ACQ6 showed significant differences between the scores before and after operation in all groups, which indicated that asthma symptoms got relieved after operation （ P 〈 0.05 ）. And the group comparison results are not statistically significant （ P 〉 0. 05 ）. Conclusions Symptoms of asthma can be relieved significantly via surgical treatment of accompanied nasal diseases. Combined application of nasal function examination and ACQ6 may provide a new strategy for the diagnosis and treatment of nasal diseases-combined asthma.