白癜风光疗疗效与临床的关系

Relationship between the efficacy of phototherapy and clinical factors in patients with vitiligo

白癜风是一种色素脱失性疾病，以皮肤或黏膜色素减退为特征，多为后天发病，可见于任何年龄，以青壮年多见，部：分患者有明显的季节性，一般春末夏初病情加重，冬季缓解。任何部位均可发病，但好发于暴露部位。该病治疗困难，影响美观，给患者带来精神心理压力。目前运用较广泛的有308nm准分子激光、窄谱中波紫外线和氦氖激光等，临床应用发现，光疗的疗效与白癜风分型、部位、病程、治疗次数、皮肤类型和红斑反应等相关。

Vitiligo is a pigmentary disorder characterized by cutaneous or mucous hypopigmentation. It is usually acquired, and ma y occur at any age, but is more common in young adults. In some patients with vitiligo, the condition gets worse at late spring and early summer, but better in winter. It may affect any body sites with a predilection for exposed sites. Vitiligo can bring psychical and mental stress to patients by affecting their appearance, however, it still remains difficult to treat. At present, commonly used phototherapy for vitiligo includes 308-nm excimer laser, narrow band-ultraviolet B, helium neon laser, etc. Clinical practice has suggested that the efficacy of phototherapy is associated with the type, site, clinical course of vitiligo, as well as treatment sessions, skin type,s and erythema reaction of patients.