膳食纤维与肠易激综合征

Dietary Fiber and Irritable Bowel Syndrome

肠易激综合征(IBS)为常见功能性肠病,临床表现多样,严重影响患者生活质量,消耗大量医疗资源。饮食调整是IBS的重要治疗手段之一。膳食纤维一般指食物中不被人体小肠内源性酶水解的碳水化合物聚合物,具有增加粪便容积的作用。很多研究探讨了增加膳食纤维摄入对IBS的影响,但尚无明确结论。多数研究认为不溶性纤维对IBS症状无益,而可溶性纤维则有一定作用。分别研究不溶性和可溶性纤维对不同IBS亚型作用的设计良好的大样本随机对照试验有待开展。

Irritable bowel syndrome（IBS） is a commonly seen functional intestinal disorder with a range of symptoms,which significantly affects patients’ quality of life and contributes to a large share of healthcare resource consumption.Diet change is an important management strategy for IBS.Dietary fiber is generally defined as carbohydrate polymers that are not hydrolyzed by the endogenous enzymes in small intestine of humans,and is effective in bulk forming.Many investigators have studied the effect of supplement of dietary fiber on IBS,but the results are often contradictory.In most studies the insoluble fiber has no beneficial effect on IBS symptoms,while the soluble fiber sometimes is effective.Well designed large sample randomized controlled trials are needed to assess the effect of insoluble and soluble fiber on different IBS subtypes. 【Key Words】： Dietary Fiber Irritable Bowel Syndrome Therapy