双呼吸导航门控高分辨黑血磁共振序列冠状动脉管壁成像

Clinical Value of Double Respiratory Navigator-gated High-resolution Black-blood Coronary Artery Wall Magnetic Resonance Imaging

目的探讨相位排序自动门控窗选择(PAWS)及同时多重容积(SMV)算法双呼吸导航门控高分辨黑血磁共振(MR)序列对冠状动脉管壁的显示效能。方法志愿者21名,行右冠状动脉(RCA)及左前降支(LAD)横断面高分辨黑血MR检查,将图像质量进行定性分级(0级=无法评价,1级=较差,2级=较好,3级=很好)。排除0级和1级图像,2级和3级进一步测量RCA和/或LAD管壁厚度,两者差异采用独立样本t检验进行评价。结果全部38幅图像中,14幅为2级,17幅为3级,RCA及LAD管壁厚度分别为(0.94±0.16)和(0.89±0.15)mm,差异无统计学意义(t=-0.790,P>0.05)。结论 PAWS及SMV算法双呼吸导航门控高分辨黑血MR序列在冠状动脉管壁成像方面具有初步临床应用价值和可行性。

Objective To explore the value of phase ordering with automatic window selection （PAWS） and simultaneous multiple volume （SMV） algorithm double respiratory navigator-gated two-dimen- sional （2DNAV） dual inversion recovery （DIR） fast spin echo （FSE） high-resolution black-blood coronary artery wall magnetic resonance imaging （MRI） and evaluate its advantages and limitations. Methods PAWS and SMV 2DNAV DIR FSE high-resolution black-blood MRI was performed in 21 healthy volunteers. The images were evaluated qualitatively by using four grades （grade 0： can not evaluate; grade 1： bad; grade 2： good; grade 3 ： perfect） . Images defined as grade 0 and grade 1 were excluded and those defined as grade 2 and 3 were evaluated further. Thickness of proximal （ or middle） segment of right coronary artery （RCA） and left anterior descending branch （LAD） were measured. The difference of wall thickness was analyzed by using two-tailed inde- pendent sample t-test. P values of less than 0. 05 were considered statistically significant. Results Among the 38 slice images, 31 slices （RCA： 13 slices, LAD： 18 slices; grade2：14 slices, grade3：17 slices） were obtained for further evaluation. The mean thickness of RCA and LAD was （0. 94 ±0. 16） and （0. 89 ±0. 15） mm, respectively, and the difference was not significant （t = - 0. 790, P 〉 0. 05） . Conclusion PAWS and SMV algorithm 2DNAV DIR FSE high-resolution black-blood MRI has certain clinical value for coronary artery wall imaging.