摘要
患者女,46岁。全身反复红斑、水疱伴痒6年,加重20d。皮损组织病理示:表皮下水疱,其内中性粒细胞聚集成小脓肿,真皮内散在淋巴细胞浸润。皮损边缘组织直接免疫荧光示:真皮乳头浅层纤维素样IgA,IgM,C3沉积。诊断:疱疹样皮炎。予糖皮质激素、四环素等治疗好转出院。随访3年无复发,目前仍在随访中。
A 46-year-old female presented with 6-year history of recurrent erythema and blisters all over her body along with intense itching, and aggravated for 20 days. Histopathological examination showed that there were blisters in subepidermis, where neutrophile granulocytes flocked together as small abscesses, and a few lymphocytes scattered in dermis. Direct immunofluorescence （DIF） showed fibrillar deposition of IgA, IgM, C3 at the papillare cutis and without IgG. Diagnosis： dermatitis herpetiformis. The marked improvement was observed with treatment of glucocorticoids and tetracycline, and now the patient is still in follow-up.
出处
《中国皮肤性病学杂志》
北大核心
2013年第7期706-708,共3页
The Chinese Journal of Dermatovenereology
关键词
疱疹样皮炎
Dermatitis herpetiformis
