质性研究与SF-36量表联用评价慢性乙型病毒性肝炎肝硬化患者的生活质量

Assessment of healthy related quality of life in patients with HBV induced liver cirrhosis

目的 探讨质性研究与SF-36两种不同研究方法联用对慢性乙型肝炎肝硬化晚期患者生存质量相关因素影响.方法 选取2009年1月至2012年1月曾在深圳市第三人民医院住院治疗的103例慢性乙型肝炎肝硬化患者为研究对象,对其进行Child分级分组,采用国内目前最常用的SF-36量表进行问卷调查,然后随机抽取其中60例采用现象学分析法调查.结果 慢性乙型肝炎肝硬化患者的生活质量与Child分级相关,各组总体健康、活力、社会功能、心理健康四项评分具有统计学差异（P＜0.05）.深度访谈发现疾病影响、心理负担、社会需求为三个主要影响生活质量的因素.结论 质性研究与SF-36量表联用能够更好的了解慢性乙型肝炎肝硬化患者的生活需求,为后续提供针对性的医护服务提供参考.

Objective To assess healthy related quality of life in patients with HBV induced liver cirrhosis.Methods A total of 103 cases of patients with HBV induced liver cirrhosis were recruited from shenzhen Third People＇s Hospital during January 2009 to January 2012.The health related quality of life were assess using the most commonly used SF-36 scale questionnaire in all 103 patiemts.Sixty patients were further chosen for health related quality assessment using qualitive research method.Results The quality of life of chronic hepatitis B patients with cirrhosis Child classification,four score of each group general health,vitality,social functioning,mental health was statistically significant （P ＜ 0.05）.Depth interviews found that the disease affects the psychological burden of the social needs of the three major affect quality of life factors.Conclusion Qualitative research with the SF-36 scale associated to a better understanding of the needs of life of patients with chronic hepatitis B cirrhosis,provide a reference for subsequent targeted medical services.