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ECHS1的表达异常与临床的关系 被引量：3

Relationship between the Abnormal Expression of ECHS1 and Clinical Diseases
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摘要 烯脂酰辅酶A水合酶短链1（ECHS1）是催化脂肪陵分解代谢β氧化第二步的关键酶，主要位于线粘体胞质内。研究发现其表达异常与代谢性疾病有关，其至与炎症性肠病及恶性肿瘤的发生、发展父系密切，现对其生物学特性及功能作一综述。 The protein encoded by enoyl coenzyme A hydratase short chain 1 （ECHS1） is the key enzyme in the second step of the mitochondrial fatty acid β-oxidation. It is pre.dominately located in the mitochondria. The abnormal expression of ECHS1 has been related to metabolic diseases, inflammatory bowel disease, and the initiation and development of cancer. In this paper, the biological characteristics and functions of ECHS1 are reviewed.
作者 朱小三 戴益琛
机构地区 厦门大学附属成功医院消化内科 南昌大学研究生院医学部
出处 《医学分子生物学杂志》 CAS 2013年第3期184-186,共3页 Journal of Medical Molecular Biology
基金 破门市科技计划医疗卫生创新项目（No.3502720124029）
关键词 ECHS1 生物学 肿瘤 脂肪酸 ECHS1 biology tumor rally acids
分类号 R34 [医药卫生—基础医学]
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参考文献24

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医学分子生物学杂志
2013年 第3期

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