氟比洛芬酯注射液超前镇痛在小儿包皮手术中的疗效观察

The experience of preemptive analges of Flurbiprofen axetilia in pediatric circumcision

目的观察氟比洛芬酯注射液超前镇痛用于小儿包皮环切术的镇痛效果及安全性。方法小儿包皮环切术50例随机分两组:A组予0.2%利多卡因2ml局部浸润麻醉,B组局部浸润0.2%利多卡因2ml联合缓慢静脉注射氟比洛芬酯注射液1mg/kg。术后1、4和8h记录FLACC评分;监测试验过程中血压、心率、呼吸频率、SpO2,并观察术后恶心呕吐的发生情况。结果与A组比较,B组各时点FLACC评分降低(P<0.05)。两组镇痛优良率均达90%以上,且差异无统计学意义(P>0.05)。结论氟比洛芬酯注射液超前镇痛比术后应用能有效减轻患儿术后疼痛,且无明显不良反应,可安全用于小儿术后镇痛。

Objective To observe the efficacy and safety of preemptive analgesia of flurhiprofen axetil injection in children circumcision. Methods 50 cases were randomly divided into 2 groups, group A O. 2% lidocaine 2 ml local anesthesia, group B 0. 2% lidocaine 2ml local anesthesia joint slow intravenous flurbiprofen axetil injection of ling / kg. Postoperative 1, 4 and 8 h record the FLACC ratings blood pressure, heart rate, respiratory rate, SpO2, and observed postoperative nausea and vomiting in the process of monitoring tests. Results Compared with group A, at each check point B group＇ s FLACC score was significantly lower （P 〈 0.05） . Two sets of the analgesic excellent rates were more than 90% , and the difference was not stats istically significant （P 〉 0. 05） . Conclusion Flurbiprofen axetil injection can effectively and safely reduce postoperative pain in children, and no significant adverse reactions.