高原地区混合痔患者手术后使用甲硝唑180例临床观察

Plateau region anorectal disease after surgery using Metronidazole of 180 cases of patients randomized controlled study

目的:观察在肛肠手术后使用甲硝唑多少天对预防术后感染是最有效。方法:采用随机、双肓和对照的方法,将180例混合痔手术患者,混合痔采用外剥内扎术[1],全部手术均采用局部浸润麻醉。术后患者按连续使用甲硝唑,使用时间,随机分为3天组、7天组和10天组。比较三组的术后感染的恢复情况。结果:7天组在术后感染的控制明显优于对3天组,其差异具有统计学意义(P>0.05);10天组与7天组术后感染无显著性差异,差异无统计学意义。用药期间,三组均无明显毒副反应发生。结论:痔疮手术后连续7天使用甲硝唑可以较好的控制术后感染。

Objective： To observe after anorectal surgery using metronidazole how many days is the most effective prevention to postoperative infection. Method： using randomized, double -blind and Comparison method, 180 cases of patients of hemorrhoids sur- gery, All patients were continuous using metronidazole, they were According to randomly divided into three groups divided into a 3 days group, 7 days group, 10 days group to compare the recovery of the three groups postoperative infection, the mixed hemorrhoids Milligan surgery; All operations were performed using local anesthesia. Results： 7 days group postoperative infection control significantly better than the 3 - day group, the difference was statistically significant; 10 days group and 7 days group postoperative infection was no signif- icant difference, the difference was not statistically significant. During the treatment, the three groups had no significant toxicity oc- curred. Conclusion ： after hemorrhoids surgery continuous use Metronidazole for 7 days can better control postoperative infection.