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氨甲喋呤(MTX)用于输卵管妊娠腹腔镜保守手术中的临床观察

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摘要 目的:以输卵管妊娠拟行腹腔镜保守手术的患者为对象,观察腹腔镜下保守手术局部应用甲氨蝶呤(MTX)的治疗效果。方法:选取输卵管妊娠需行腹腔镜下保守性手术的患者150例,随机分为2组,A组75例采用腹腔镜保守手术,术中取胚后使用MTX 25mg(注入输卵管内)。B组75例采用腹腔镜保守手术,不注射MTX。观察两组PEP的发生率及药物毒副反应。结果:A组术后PEP发生1例,B组术后发生7例,发生率为9.3%,B组术后PEP发生率明显高于A组,两组的PEP发生率差异有统计学意义(P<0.05)。结论:腹腔镜下输卵管妊娠保守手术治疗,术中局部使用MTX可有效防止持续性异位妊娠的发生,值得临床推广。
作者 朱林
出处 《中国民族民间医药》 2013年第11期81-81,83,共2页 Chinese Journal of Ethnomedicine and Ethnopharmacy
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