胰岛素全程治疗糖尿病合并肺结核的疗效分析

Efficacy of insulin throughout the treatment of diabetes and tuberculosis

目的 探讨胰岛素全程治疗糖尿病合并肺结核患者的疗效和安全性.方法 100例2型糖尿病（T2DM）合并肺结核患者在常规应用抗结核药物治疗的同时,随机分为胰岛素（门冬胰岛素30注射液）治疗（观察组52例）和口服降糖药治疗（对照组48例）,比较治疗后两组的血糖达标时间、低血糖发生率、痰菌转阴情况及肺结核病灶X线变化.结果 治疗观察组的临床症状改善、胸片转归及血糖达标时间明显优于对照组.结论 糖尿病合并肺结核患者降糖首选方案为胰岛素（门冬胰岛素30注射液）全程控制血糖,而肺结核化疗疗效与血糖控制水平密切相关.

Objective Explore the efficacy and safety of insulin throughout the treatment of diabetes and tuberculosis patients.Methods 100 patients with type 2 diabetes mellitus （T2DM） patients with pulmonary tuberculosis in the routine application of anti-TB drugs standardization were randomly divided into treatment of insulin （Insulin aspart 30 injecton）） observation group,52 cases and 48 cases of oral antidiabetic treatment control group,comparing the treatment of the two sets of blood glucose time,the incidence of hypoglycemia,sputum negative situation and tuberculosis lesions in x-ray changes.Results Insulin （Insulin aspart 30 injecton） treatment observation group improvement of clinical symptoms,chest X-ray outcome and blood glucose was significantly superior to oral medication group.Conclusion Diabetic patients with pulmonary tuberculosis hypoglycemic preferred solution for insulin （Insulin aspart 30 injecton） full control blood sugar,tuberculosis chemotherapy is closely related to the level of blood sugar control.