期刊文献+

下肢深静脉血栓溶栓治疗时血浆D-二聚体水平的临床意义 被引量:5

下载PDF
导出
摘要 目的探讨下肢深静脉血栓溶栓治疗时血浆D-二聚体水平的临床意义。方法选取2008年6月至2012年6月我院接收的94例下肢深静脉血栓患者作为研究对象,分别于患者人院时,经过溶栓治疗1d、1周、2周以及结束时测定患者的D-二聚体水平、患肢周径以及血栓治疗情况。结果所有经过溶栓治疗的患者的下肢肿胀情况得到改善,入院时患者的D-二聚体水平高于正常范围,经过溶栓治疗1d后D-二聚体水平增高,两者相比具有统计学意义俨〈0.01);治疗后1周、2周逐渐下降,直至治疗结束时D-二聚体水平方达到正常范围;三组数据进行对比均有统计学意义(P〈0.01)。治疗结束时利用多普勒彩超发现DVT患者中12例全部再通,36例部分再通。结论D-二聚体的测量可以作为确诊下肢静脉血栓的-项指标,但特异性较低,需辅助其他方式确诊,临床上进行溶栓治疗时可以通过测定D-二聚体的水平指导合理用药,且为治疗方案提供参考。
出处 《国际医药卫生导报》 2013年第14期2184-2185,共2页 International Medicine and Health Guidance News
  • 相关文献

参考文献8

二级参考文献49

  • 1曹艳,刘昱升,沈晓凤.硬膜外分娩镇痛对产妇血浆D-二聚体水平的影响[J].临床麻醉学杂志,2006,22(12):918-919. 被引量:9
  • 2朱元珏 赵永强 汪钟 郑植栓.静脉血栓形成[A].汪钟,郑植栓.现代血栓病学[C].北京:北京医科大学中国协和医科大学联合出版社,1997.346—347.
  • 3Kahn S R. The post-thrombotic syndrome:progress and pitfalls[J]. Br J Haematol, 2006,134(4) :357-365.
  • 4Baldwin Z K,Comerota A J, Schwartz L B. Cathere-directed thrombolysis for deep venous thrombosis[J]. Vasc Endovascular Surg, 2004,38(1):1-9.
  • 5Porter J M,Moneta G L. Reporting standards in venous disease: An update[J]. J Vasc Surg, 1995,21 (4) :635-645.
  • 6李麟孙,贺能树,邹英华.介入放射学-基础与方法[M].北京:人民卫生出版社,2005:55.
  • 7CIRSE and SIR Standards of Practice Committees. Quality improvement guidelines for the treatment of lower extremity deep vein thrombosis with use of endovascular thrombus removal[J]. J Vasc Interv Radiol, 2006,17(3) :435-448.
  • 8Macedo T, Bjarnason H. Catheter directed thrombolysis: overview and update from SCVIR [J]. Applied Radiology, 2002,31(8) :73.
  • 9Anthony J,Comerota A,Zakaria F, et al. Technique of catheter-directed thrombolysis. Rutherford Vascular Surgery [M]. Sixth ed, 2005:2181-2184.
  • 10Janssen M C H,Wollershein H, Schultze kool L J, et al. Local and systemic thrombolytic therapy for acute deep venous thrombosis[J].Neth J Ailed, 2005,63(3) :81-90.

共引文献84

同被引文献40

  • 1矢永尚士.心血管疾病与气象、季节.日本医学介绍,1986,7(1):23-24.
  • 2蒙秀林,张颖,马刚.围产期深静脉血栓形成21例临床分析[J].海南医学,2007,18(11):101-103. 被引量:4
  • 3Qiu xs, Wang F, Yao C, et al. Association between deep vein thrombosis and the temperature at the popliteal fossa during cement curing in total knee arthroplasty[J].J Arthroplasty, 2011, 26(3): 414-418.
  • 4Gubler DJ, Reiter P, Ebi KL, et al. Climate variability and change in the United States: potential impacts on vector- and rodent-borne diseases[J].Environ Health Perspect, 2001, 109 Suppl 2: 223-233.
  • 5Damnjanovic Z, Jovanovic M, Stojanovic M. Correlation between the climatic factors and the pathogenesis of deep vein thrombosis[J].Hippokratia, 2013, 17(3): 203-206.
  • 6Nimako K, Poloniecki J, Draper A, et al. Seasonal variability and meteorological factors: retrospective study of the incidence of pulmonary embolism from a large United kingdom teaching hospital[J].Respir Care, 2012, 57(8): 1267-1272.
  • 7Fares A.Winter cardiovascular diseases phenomenon[J].N Am J Med Sci, 2013, 5(4): 266-279.
  • 8Kearon C, Akl EA, Comerota A J, et al. Antithrombotic therapy for VTE disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines[J].Chest, 2012, 141(2Suppl): e419S-494S.
  • 9Enden T, Haig Y, Klow NE, et al. Long-term outcome after additional catheter-directed thrombolysis versus standard treatment for acute iliofemoral deep vein thrombosis (the CaVenT study): a randomisedcontroUedtrial[J].Lancet, 2012, 379(9810): 31-38.
  • 10Schleich JM, Morla O, Laurent M, et al. Long-term follow-up of percutaneous vena cava filters: a prospective study in 100 consecutive patients[J].EurJVasc Endovasc Surg, 2001, 21(5): 450-457.

引证文献5

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部