不同治疗方案在真菌性鼻-鼻窦炎治疗中的临床疗效分析

The Clinical Efficacy of Different Treatment Regimens in the Treatment of Fungal Nasal-sinusitis

目的:探讨不同手术治疗方案在真菌性鼻-鼻窦炎(FRS)治疗中的临床疗效。方法:将本院收治的78例FRS患者随机分为两组。对照组给予鼻内镜手术治疗,术中采用生理盐水冲洗鼻窦腔,观察组在此基础上改用抗真菌药物冲洗鼻窦腔,观察两组患者的临床疗效和预后情况。结果:观察组8个月后VAS评分为(0.68±0.07)分,Lund-Kennedy评分为(0.57±0.16)分,临床总有效率为91.1%(41/45),对照组VAS评分为(1.72±0.09)分,Lund-Kennedy评分为(1.25±0.39)分,临床总有效率为69.7%(23/33),两组差异有统计学意义(P<0.05)。结论:鼻内镜手术联合抗真菌药物冲洗鼻窦腔能显著提高FRS的临床治疗效果,改善临床症状,具有重要的临床应用价值。

Objective：To explore the clinical efficacy of different surgical treatment in the treatment of fungal nasal-sinusitis. Method：78 patients were randomly divided into two groups in our hospital,the control group was treated with endoscopic sinus surgery,saline was used to flush the sinus cavities,the observation group were treated with antifungal agents flush the sinus cavities,the clinical efficacy and prognosis was observed. Result： Lund-Kennedy score of the observation group was（0.57±0.16）,the score of VAS was（0.68±0.07）,the total effective rate was 91.1%（41/45）, Lund-Kennedy score of the control group was（1.25±0.39）,the score of VAS was（1.72±0.09）,the total effective rate was 69.7%（23/33）,the difference was statistically significant（P ＆lt;0.05）. Conclusion：Antifungal rinse the sinus cavities can significantly improve the clinical efficacy of endoscopic sinus surgery,it has important clinical value.