期刊文献+

布地奈德和异丙托溴铵氧驱动雾化吸入治疗毛细支气管炎临床疗效观察 被引量:6

Budesonide and Ipratropium Bromide Oxygen Drive Atomization Inhalation on Bronchiolitis Clinical Curative Effect Observation
下载PDF
导出
摘要 目的:观察布地奈德和异丙托溴铵氧驱动雾化吸入治疗毛细支气管炎的临床疗效。方法:将68例毛细支气管炎患儿随机分为两组,两组均给予常规治疗,在此基础上,观察组35例给予布地奈德和异丙托溴铵氧驱动面罩雾化吸入。对照组33例给予庆大霉素、α-糜蛋白酶、地塞米松进行超声雾化吸入。疗程均为5~7d,2次/d,观察两组的疗效。结果:观察组总有效率为97.14%,高于对照组的66.67%,差异有统计学意义(P<0.01)。结论:布地奈德和异丙托溴铵氧驱动雾化吸入治疗毛细支气管炎疗效明显高于对照组,且缩短了疗程,药物全身不良反应小,更简便易行,值得临床推广应用。 Objective:To observe the effect of budesonide and ipratropium bromide oxygen atomizing inhalation to treat bronchiolitis clinical curative effect.Method:68 cases of bronchiolitis were randomly divided into 2 groups,two groups were given routine treatment,the observation group 35 cases were given budesonide,ipratropium bromide oxygen drive atomization inhalation mask too.33 patients of control group were given gentamicin too,chymotrypsin,ultrasonic atomizing inhalation of dexamethasone.Treatment lasted for 5-7 days,2 times/day,curative effect of the two groups were observed.Result:In the observation group,the total efficiency was 97.14%,it’s higher than 66.67% in the control group,the difference was statistically significant(P &lt;0.01).Conclusion:Budesonide and ipratropium bromide oxygen atomizing inhalation treatment of bronchiolitis is significantly higher than that of the control group,and shorten the course of treatment,the general drug adverse reactions.it’s more convenient,and worthy of clinical application.
作者 任畅 霍晓露
出处 《中国医学创新》 CAS 2013年第19期50-52,共3页 Medical Innovation of China
关键词 毛细支气管炎 氧驱动雾化吸入 布地奈德 异丙托溴铵 超声雾化吸入 Bronchiolitis Oxygen atomizing inhalation Budesonide Ipratropium Ultrasonic atomizing inhalation
  • 相关文献

参考文献9

二级参考文献41

  • 1黄荣妍,陈慧中,耿学辉,钱渊,王之梁,张梓荆.呼吸道合胞病毒毛细支气管炎血清维生素A水平的变化[J].中华儿科杂志,1996,34(6):372-375. 被引量:22
  • 2中华人民共和国卫生部.小儿肺炎防治方案[J].中华儿科杂志,1987,25:47-47.
  • 3许积德主编.小儿内科学 第3版[M].北京:人民卫生出版社,1994.150~151.
  • 4Nadel JA, Takeyama K, Augusti C. Role of neutrophil elastase in hypersecretion in asthma [J]. Eur Respir J, 1999, 13(1):190-196.
  • 5Emboriadou M, Hatistilianou M, Magnisali CH, et al. Human neutrophil elastase in RSV bronchiolitis [J]. Ann Clin Lab Sci, 2007,37 ( 1 ) : 79-84.
  • 6Bennett BL, Garofalo RP, Cron SG, et al. Immunopatho-genesis of respiratory syncytial virus bronchiolitis [J]. J Infect Dis ,2007,195 (10) :1532-1540.
  • 7Yasui K, Baba A,Iwasaki Y, et al. Neutrophil-mediated inflammation in respiratory syncytial viral bronchiolitis [J]. Pediatr Int, 2005, 47 (2):190-195.
  • 8Jaovisidha P, Peeples ME, Brees AA, et al. Respiratory syncytial virus stimulates neutrophil degranulation and chemokine release [J]. J Immunol,1999,163 (5) :2816- 2820.
  • 9Wang SZ, Smith PK, Lovejoy M, et al. Shedding of L- selectin and PECAM-1 and upregulation of Mac-1 and ICAM-1 on neutrophils in RSV bronchiolitis [J]. Am J Physiol, 1998, 275(5 Pt 1) :L983-L989.
  • 10Teran LM, Johnston SL, Schroder JM, et al. Role of nasal interleukin-8 in neutrophil recruitment and activation in children with virus induced asthma [J]. Am J Respir Crit Care Med, 1997,155 (4) : 1362-1366.

共引文献422

同被引文献78

引证文献6

二级引证文献31

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部