摘要
使用Salen Co(Ⅱ)配合物催化氧化百里酚制备百里醌,考察了不同的反应条件对催化体系的影响。确定该合成工艺的最佳条件为以氧气为氧化剂,10%mol Salen Co(Ⅱ)配合物为催化剂,在DMF溶液中30℃反应9h,收率可达99.1%。该工艺具有反应选择性好、反应条件温和、收率高和后处理操作简单等特点,适合于工业化生产。
Thymoquinone was prepared from catalytic oxidation of thymol by Salen Co (Ⅱ) complex. The best reaction oxidation conditions of thymol were optimized by investigating the effect of different reaction conditions on the catalytic system. The reaction was carried on 9 hours in the DMF solution under 30 ℃, oxygen as oxidant and 10% mol Salen Co (Ⅱ) complex as catalyst. This method was suitable for industrial production because it prossessed some advantages such as high selectivity, mild reaction conditions, high efficiency and simple to operate.
出处
《黑龙江大学工程学报》
2013年第2期38-41,共4页
Journal of Engineering of Heilongjiang University
基金
哈尔滨市科技创新人才研究专项资金项目(RC2012XK001005)