873例肺部感染病原菌分布及耐药性分析

Analysis of pathogen distribution and drug resistance of 873 cases of lung infection

目的研究本地区肺部感染病原菌分布及耐药情况。方法对我院873株病原菌培养阳性患者菌群分布及药敏试验进行分析。结果 873株病原菌菌株分布G-杆菌464株(53.2%),以铜绿假单胞菌、鲍曼不动杆菌、肺炎克雷伯菌、大肠埃希菌感染多见;G+球菌355株(40.7%),以肺炎链球菌、金黄色葡萄球菌感染多见;真菌35株(4.0%),以白色念珠菌为主;肺部感染菌群分布G-杆菌感染呈上升态势;肺部感染病原菌对各种抗生素均有不同程度的耐药现象,亚胺培南对主要的G-杆菌及有较好的敏感性,万古霉素对主要G+球菌有较好的敏感性。结论临床抗生素的使用习惯与肺部感染菌群分布及耐药密切相关,根据药敏实验选择抗生素对临床耐药菌株的减少及治疗的有效性有重要的临床意义。

Objective To study the local pulmonary infection pathogen distribution and drug resistance of clinical antibiotics.Methods 873 strains of pathogen were cultured to analyze their distribution and drug resistance.Results There were 464 strains of Gbacilli 464（53.2%）,which included pseudomonas aeruginosa,acinetobacter baumannii,klebsiella pneumoniae,and escherichia coli.355 strains of G＋ cocci（40.7%） included streptococcus pneumoniae and staphylococcus aureus.35 strains of fungi（4.0%） mainly included candida albicans.The distribution of G-bacillus infection showed upward trend.G-bacteria was sensitive to imipenem,and G＋ cocci was sensitive to vancomycin.Conclusion The clinical use of antibiotics habits and pathogen distribution are closely related to the drug resistance.The use of antibiotics should be based on the drug sensitivity test.