48例非小细胞肺癌再程放疗临床探究

Clinical study on re-course radiotherapy in 48 patients with non-small cell lung carcinoma

目的探究非小细胞肺癌再程放疗的临床效果。方法收集我院非小细胞肺癌复发48例,再次放疗距初次放疗时间为19.1±8.6周。分为观察组与对照组,观察组患者进行辅助化疗1～6周期后给予再程放疗,对照组只进行辅助化疗,观察患者的存活率。结果观察组的患者治疗三个月后复查胸部CT,CR2例;PR17例;SD为3例;PD为2例,有效率为70.8%,远高于对照组。48例中1年生存率63%,中位生存时间为10.5个月。接受再程放疗的患者均有较高的存活率。结论再程放疗能较安全地应用于非小细胞肺癌,疗效较好,不良反应较轻,值得进一步推广应用。

Objective To explore the clinical effects of radiotherapy method for non-small cell lung cancer and then drive collected in our hospital from January 2009 to February 2012,48 cases of non-small cell lung cancer recurrence again radiotherapy from the initial time of radiotherapy was 19.1 ± 8.6 weeks.Divided into observation group and the control group,the observation group were 1-6 cycles of adjuvant chemotherapy given after again away radiotherapy,the control group only adjuvant chemotherapy,observe the patient＇s survival.Review of chest CT results of the observation group of patients treated for three months,CR2 patients;PR17 Example 3 cases;SD;PD for the two cases,the effective rate was 70.8%,far higher than the control.1-year survival rate was 63% in 48 cases,the median survival time was 10.5 months.To accept the re-course radiotherapy patients had a higher survival rate.Conclusion re-course radiotherapy can be safely used in non-small cell lung cancer,better efficacy and less adverse reactions,it is worth further promote the application