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基于体素形态学的中风偏瘫患者脑皮层结构研究 被引量:4

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摘要 目的针对中风偏瘫运动功能障碍,采用基于体素形态学(voxel-based morphometry,VBM)的方法,研究脑运动相关皮层结构变化。方法采用对照研究方法,分为偏瘫组和正常组,将符合纳入条件的受试者分别进行核磁成像扫描,采集高分辨率结构像,对图像数据结构采用体素形态学方法进行统计分析。结果与正常组对比,偏瘫组在运动皮层有体素减少,主要集中于左侧后顶叶运动皮层,双侧前额叶皮层也出现了明显的体素减少,在左侧小脑皮层有体素增长。结论中风偏瘫患者在非病灶部位的大脑运动相关皮层以及小脑皮层结构出现萎缩或增长,反映了皮层变化可能与患者大脑运动执行功能下降以及小脑的运动调节功能代偿机制有关,也为脑损伤后脑运动功能恢复提供了新的试验依据。
出处 《中西医结合心脑血管病杂志》 2013年第7期779-781,共3页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
基金 国家自然科学基金课题面上项目(No.81072773)
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参考文献13

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共引文献70

同被引文献79

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