中心性肥胖对原发性高血压左室肥厚的影响

Impact of Central Obesity on Left Ventricular Hypertrophy in Essential Hypertension

目的探讨中心性肥胖对原发性高血压患者左室肥厚的影响。方法采用前瞻性队列研究方法,以2010年3月—2012年4月于我院心血管内科门诊就诊的340例原发性高血压患者作为观察队列,按照国际糖尿病联盟设定的亚洲人中心性肥胖的诊断标准,将其分为中心性肥胖组和对照组。通过二维引导的M模式进行测量记录左心室结构,计算左心室质量指数及左室肥厚在两组的发生率,比较中心性肥胖与左室肥厚间的相关性。结果中心性肥胖组患者的左心室质量指数显著高于对照组,且左室肥厚的发生率明显高于对照组(P<0.05)。结论除血压水平外,中心性肥胖与高血压患者的左室肥厚发生密切相关。

Objective To investigate the impact of central obesity on the development of left ventricular hypertrophy in an essential hypertension. Methods three hundreds and forty patients with essential hypertension was diagnosed and were further classified into central obesity and control groups according based on the International Diabetes Federation criteria. Baseline anthropometric and labo- ratory features were obtained by physical examination. The left ventricular structure and left ventricular mass index were measured by M mode echocardiography. The levels of left ventricular mass index and left ventricular hypertrophy prevalence rates were com pared. Results The levels of left ventricular mass index and left ventricular hypertrophy prevalence rates were higher in central obesi- ty group than that in control group. The data was statistically significant. Conclusion Apart from the blood pressure, central obesity played an important role in the development of left ventricular hypertrophy in Patients with essential hypertension.