将科研思维和实践引入研究生蛋白质组学教学的尝试

Inducing scientific thinking and practice in the proteomics course for postgraduates

为了将理论知识内容与实际研究工作相结合，授课教师将科研思维和实践引入研究生的蛋白质组学课程教学中。如，为让学生真正了解2-DE蛋白分离技术，在讲授经典的2-DE技术基础上，结合实例用图示指出经典2-DE技术存在的问题和局限，再用改进的2-DE蛋白分离图谱，剖析如何在实际工作中加以应用；为提高研究生的科研思维能力，以肿瘤为实例，要求各专业的研究生查阅相关文献、提出科学问题、设计课题、寻求答案。通过这些教学尝试，探索能力型医学人才培养路径。

Teachers introduced the means of the scientific thinking and scientific research prac- tice in the curriculum of proteomics in order to train the postgraduates to joint the theory and the practical research work in the curriculum course. For example, to cultivate students to truly understand the 2-DE protein separation technique, teachers used the various proteomic profile obtained from our research to points out its problems and limitations based on the classical 2-DE, then compared the improved 2-DE protein separation chromatography with the classical 2-DE graphic and analyzed what is the problem and how to solve them in the practical work. To improve the ability of scientific thinking for postgraduates, teachers took the tumor as the teaching cases and asked the postgraduates to search the referenees of can- cer associated with their professional, to put forward the scientific problems based on carefully reading these references, to design their research project and to seek the answer to their issue. These new teaching methods were found to be beneficial in training scientific talents of medical postgraduates.