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不同剂量阿司匹林治疗短暂性脑缺血发作的临床疗效观察 被引量:4

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摘要 目的:比较不同剂量阿司匹林治疗短暂性脑缺血发作的临床疗效。方法:将108例短暂性脑缺血发作患者分为观察组和对照组,每组根据ABCD2评分划分危险度分层,观察组给予阿司匹林肠溶片300 mg,1次/d,连用7 d;对照组给予阿司匹林肠溶片100 mg,1次/d,7 d后两组均常规剂量100 mg,1次/d,两组随访至第30天。结果:观察组第7天有效率为94.44%,对照组有效率为79.63%,两组比较有统计学意义(P<0.05);第30天观察组有效率为87.04%,对照组有效率为68.52%,两组比较有统计学意义(P<0.05)。各组危险度分层比较治疗疗效也有统计学意义(P<0.05)。结论:早期对短暂性脑缺血发作患者进行危险度分层,并采取有效的治疗可显著减少脑梗死的发生。
出处 《吉林医学》 CAS 2013年第19期3845-3846,共2页 Jilin Medical Journal
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  • 1各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33008
  • 2Antiplatelet Trialist' Collaboration. Collaborative overview of randomized trials of antiplatelet therapy- Ⅰ - Ⅲ[ J ]. BMJ, 1994 ;308 (6921-6923 ) : 81- 106,159-68,235-46.
  • 3Antiplatelet Trialist's Collaboration. Collaborative overview of randomized trial of antiplatelet therapy, Ⅰ: prevention of death, myocardial infarction, and stroke by prolonged antiplatet therapy in various categoties of patients BMJ, 1994 ;308 (6921) :81-106
  • 4Helgason CM, Bolin KM, Hoff JA, et al. Development of aspirin resistance in persons with previous ischemic stroke [ J ]. Stroke, 1994 ;25:2331-6.
  • 5Pappas JM, Westengard JC, Bull BS. Population variability in the effect of aspirin on platelet function: implication for clinical trials and therapy [J]. Arch Pathol Lab Med,1994;118:801-4.
  • 6Grotemeyer KH, Scharafinski HW, Husstedt IW. Two-year follow-up of aspirin responder and aspirin non-responder: a pilot-study including 180 post-stroke patients [J]. Thromb Res, 1993 ;71 : 397-403.
  • 7Gum PA, Kotike-Marchant K, Poggio ED, et al. Profile and prevalence of aspirin resistance in patients with cardiovascular disease[ J]. Am J Cardiol,2001 ;88:230-5.
  • 8Weber AA, Przytulski B, Schanz A, et al. Towards a definition of aspirin resistance : a typological approach [ J ]. Platelets, 2002 ; 13 ( 1 ) : 37 -40.
  • 9Gum PA, Kottke-Marchant K, Welsh PA, et al. A Prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease[ J]. J Am Coll Cardiol,2003 ;41:961-5.
  • 10Lee PY, Chen WH, Ng W, et al. Low-dose aspirin increases aspirin resistance in patients with coronary artery disease [ J ]. Am J Med,2005;118: 723 -7.

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  • 1中国缺血性脑卒中和短暂性脑缺血发作二级预防指南2010[J].中国医学前沿杂志(电子版),2011,3(3):84-93. 被引量:83
  • 2陈健华,王建明,崔丽英,陈琳.阿司匹林与脑出血危险性的关系[J].中风与神经疾病杂志,2007,24(2):196-198. 被引量:25
  • 3李晓卫.阿司匹林与高血压脑出血术后再出血的相关性[J].临床神经病学杂志,2007,20(6):463-464. 被引量:14
  • 4安宁, 解锦鼎, 杨晓帆. 辛伐他汀联合阿司匹林治疗急性缺血性脑卒中的疗效观察[J]. 中国药物经济学. 2013, 4(04):564-566.
  • 5Wong KS, Chen C, Fu J, et al. Clopidogrel plus aspirin Veraspi-rin alone for reducing embolisation in symptomatrc; randomised,cerebral or carotid artery stenosis patients with acute ( CLAIRstudy): a open label, blinded-endpoint trial[J]. Lancet Neuro1,2010, 9(5):489.
  • 6Geraghty OC, Paul NLM, Chandratheva A, et al. Low risk ofrebound events after a short course of clopidogrel in acute TIA orminor stroke[J]. Neurology. 2010, 4 (23):1052-1054.
  • 7Goldstein LB,Bushnell CD,Adams RJ,et al.Guidelines for the primary prevention of stroke:a guideline for healthcare professionals from the American Heart Association/American Stroke Association[J].Stroke,2011,42(2):517-584.
  • 8Kobayashi K,Kishi M,Atsumi T,et al.Circulating oxidized LDL forms complexes with beta2-glycoprotein I:implication as an atherogenic auto- antigen[J].J Lipid Res,2003,44(4):716-726.
  • 9European Stroke Organisation (ESO)Executive Committee.Guidelines for management of ischaemic stroke and transient ischaemic attack 2008[J].Cerebrovasc Dis,2008,5(5):457-507.
  • 10European Association for Cardiovascular Prevention & Rehabilitation,Reiner Z,Atapano AL,et al.ESC/EAS Guidelines for the management of dyslipidaemias:the Task Force for the management of dyslipidaemias of the European Society of Cardiology(ESC)and the European Atheroscle- rosis Society(EAS)[J].Eur Heart J,2011,32(14):1769-1818.

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