儿童重症手足口病46例临床特征分析

Clinical characteristic analysis of 46 children with severe hand,foot and mouth disease

目的研究儿童重症手足口病的临床特征,为早期临床诊断提供依据。方法选取安阳市第五人民医院46例儿童重症手足口病患儿的临床资料,回顾性分析其临床诊断及临床特征。结果主要临床特征如下:皮疹及口腔溃疡46例(100%),高热45例(97.8%),中枢神经系统(CNS)症状35例(76.1%),呼吸急促24例(52.2%),支气管炎8例(17.4%),咳嗽17例(37.0%),肺水肿7例(15.2%),消化系统症状27例(58.7%),EV71感染者35例(76.1%)。结论儿童重症手足口病发病急,病情发展快,加强研究其临床特征有利于早期识别和处理危重病例,对降低病死率、改善患者预后有重要意义。

Objective To study the clinical characteristics of children with severe hand,foot and mouth disease,in order to provide evidence for early clinical diagnosis.Methods The clinical diagnosis and clinical features of 46 children with severe hand,foot and mouth disease in the fifth people’s hospital of Anyang were retrospectively analyzed.Results The main clinical features were as follows： skin rash and oral ulcer occurred in 46 cases（100%）,high fever in 45 cases（97.8%）,CNS symptoms in 35 cases（76.1%）,shortness of breath in 24 cases（52.2%）,bronchitis in 8 cases（17.4%）,cough in 17 cases（37.0%）,pulmonary edema in 7 cases（15.2%）,the digestive system symptoms in 27 cases（58.7%）.There were 35 cases（76.1%） infected by EV71.Conclusion Children with severe hand,foot and mouth disease has acute onset,and develop rapidly,to strengthen the research of the clinical features is good for early recognition and treatment of serious disease,which is significant important in reducing the mortality and improving the prognosis of patients.