益气祛瘀丸治疗气虚血瘀型缺血性中风16例

Clinical Observation on Effect of Pill of Yiqi Quyu Treatment Patients with Acute Ischemic Stroke of Blood of Stasis Due to Qi Deficiency

目的:对益气祛瘀丸治疗气虚血瘀型缺血性中风的安全性和有效性进行评估并探讨其作用机制。方法:选择2010年6月-2012年3月在九江市中医院住院的病人32例,通过随机抽样平均分为2组,治疗组给予益气祛瘀丸合用阿司匹林,对照组单用阿司匹林,2组患者其它治疗均遵照急性脑血管病治疗指南进行。结果:治疗组和对照组治疗3、14d后神经功能状态评分无显著性差异,治疗90d后治疗组和对照组Barthel指数改善有显著性差异,14d后血液流变学有显著性差异,治疗前后肝肾功能、同型半胱氨酸(hcy)没有显著性差异。结论:研究结果表明,益气祛瘀丸治疗气虚血瘀型缺血性中风是安全有效的。

Objective： In this trial, we evaluate the efficacy and safety of pill of yi qi qu yu in patients with acute ischemic stroke, and explore the mechanism of it. Methods ： We recruit 32 patients with acute ischemic stroke in Jiujiang Chinese medicine hospital between June 1, 2010 and March 1, 2012, averagely divide into two groups by a randomization table, to receive either oral pill of yi qi qu yu and aspirin tablet per day （Treat Group）or oral aspirin tablet per day （Control Group） for 90 days .Thus therapy abide by Guideline for the diagnosis and treatment of acute ischemic stroke China 2010.Resuhs： Before treatment, After administering medicine for 3 days, 14 days, there were no statistically significant differences about neurological status between treat group and control group and also no statistically significant differences about liver function kidney function and homocystinemia （ hcy） between two groups. But the general living ability（Barthel Index） after administering medicine for 90 days, hemonheologic parameters after administering medicine for 14 days, have statistically significant differences when we compared treat group to control group. Conclusion： The trial results have shown pill of yi qi qu yu in the acute ischemic stroke treatment is safe and efficacious.