摘要
目的:研究草珊瑚乙酸乙酯部位的化学成分。方法:采用硅胶、反相硅胶、Sephadex LH-20凝胶柱层析进行、制备液相等手段分离纯化,根据理化性质和光谱分析鉴定化合物结构。结果:从草珊瑚乙酸乙酯部位中分离得到了7个化合物,经鉴定分别为11,13-dihydroisolantolacton(1)、11α,13-dihydro-2α-hydroxyalantolactone(2)、santamarin.(3)、8-epi-ivangust(4)、异东莨菪素(5)、嗪皮素(6)、异嗪皮啶(7)。结论:化合物1,2,3,4为首次从该属植物中分离得到。
Objective:To study the chemical constituents from ethyl acetate extract of Sareandra glabra. Methods: Column chromatography and spectral analysis were used to isolate and identify the constituents. Results: The ethyl acetate fraction from Sarcandra glabra was separated and purified.Seven compounds were obtained and identified as:l l, 13-dihydroisolan- tolacton( 1 ), 11 a, 13-dihydro -2ct -hyd- roxyalantolactone (2), santamarin ( 3 ), 8-epi-ivangust (4), scopoletin ( 5 ), fraxetin (6) and isofraxidin (7). Conclusion: Compounds 1, 2, 3, and 4 are isolated from this genus for the first time.
出处
《北方药学》
2013年第7期15-16,共2页
Journal of North Pharmacy
关键词
草珊瑚
乙酸乙酯提取物
化学成分
Sarcandra glabra Ethyl acetate extract Chemical constituents