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肝吸虫病患者血清中Ig及C_3的测定 被引量:1

The assay of serum Ig and C_3 levels in patients with clonorchiasis
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摘要 目的 :探讨人体感染肝吸虫后机体免疫功能的状态。方法 :应用 ELISA双抗体夹心法检测肝吸虫病患者血清中总 Ig E水平 ,以单向免疫扩散法检测 3 6名肝吸虫病患者血清中 Ig G、Ig M、Ig A及 C3 的水平。结果 :肝吸虫病患者血清中总 Ig E含量为 1 1 4 6.4 0± 986.2 1 IU/ml,Ig G、Ig M和 Ig A水平分别为 1 5.1 9± 8.0 1 mg/ml、 1 .94± 1 .86mg/ml和 2 .0 4± 1 .3 9mg/ml。除 Ig A外 ,均明显高于对照组的测定值 ,而 C3 为 1 3 4 2 .5± 4 67.9mg/ml明显低于对照组。结论 Objective:To investigate the immunologic function of the patients with clonorchiasis.Methods:The total IgE level in sera from 36 cases of clonorchiasis was determined by ELISA and the total IgG,IgA,IgM and C 3 levels in sera from the patients were determined by simple immunodiffusion.Results:The total serum IgE,IgG and IgM levels of the patients with clonorchiasis were significantly higher than those of the control grorup.But the C 3 level of the patients was significantly lower than the control group.Conclusion:It is suggested that the humoral immunity may play a role in the immunomechanism of clonorchiasis.
出处 《武警医学院学报》 CAS 2000年第1期23-24,共2页 Acta Academiae Medicinae CPAPF
关键词 人体肝吸虫病 免疫球蛋白 补体 ELISA Human clonorchiasis ELISA Ig C 3
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