摘要
目的 :了解细胞因子在轮状病毒 ( RV)肠炎患儿血清中肿瘤坏死因子 ( TNFα)和白细胞介素 6( IL-6)的变化 ,探讨其在免疫调节中的机理。方法 :采用双抗体夹心 ELISA法检测了 2 2例 RV肠炎患儿血清中 TNFα和 IL-6的水平 ,同时与病情变化相比较。结果 :RV肠炎患儿急性期血清 TNFα和 IL-6水平明显升高 ,与病情呈正相关。结论 :血清 TNFα和 IL-6在
Objective:To study the changes of TNFα and IL 6 in children with rotavirus (RV) enteritis and their possible mechanism in immunoregulation Methods:The serum TNFα and IL 6 in 22 children with RV enteritis were determined by sandwich ELISA method Results:The serum TNFα and IL 6 levels in children with RV enteritis were significantly increased,and obviously correlated with the course of the disease Conclusion:It is possble that serum TNFα and IL 6 may play an important role in immunoregulating mechanism in children with RV enteritis
出处
《武警医学院学报》
CAS
2000年第1期29-30,共2页
Acta Academiae Medicinae CPAPF
