冠心丹参片薄膜包衣生产工艺研究

Study on the Production Process of Guanxin Danshen Film-coated Tablets

目的:将冠心丹参片改为薄膜衣片,提高冠心丹参片质量。方法:以胃溶型全水防潮性包衣剂为包衣料,将生产的冠心丹参薄膜衣片与冠心丹参糖衣片同时进行稳定性考察、比较。结果:冠心丹参薄膜衣片在抗湿性、硬度、稳定性、外观等均优于糖衣片。结论:操作方法简单,工艺成熟、可行。

Objective： The preparation technology of guanxin danshen tablets was reformed to change guanxin danshen tablets into film-coated tablets so as to improve the product quality. Methods： Gastric type dampproofing tunicates materials were used as the drug coating substance and the stability studies were carried out simultaneously for both guanxin danshen film-coated tablets and guanxin danshen sugarcoating tablets. Results： The guanxin danshen film-coated tablets proved better than the sugarcoating tablets in dampproofing , hardness, stability, and appearance. Conclusion： The preparation technology of guanxin danshen film-coated tablets was simple , stable and feasible.