艾滋病患者服ARV并发贫血和高脂血症的中医证候分析

Traditional Chinese Medicine Syndrome Differentiation of AIDS Patients on ARV Complicated with Anemia and Hyperlipidemia

目的:通过分析艾滋病患者经HAART治疗后并发贫血和高脂血症的中医四诊信息,探讨其证候特点及共同病机。方法:采用病例回顾性方法,以国家"十一五"重大专项某课题病例资料为来源,艾滋病患者经HAART治疗,对其中医四诊信息进行统计分析。结果:艾滋病患者合并贫血或高脂血症出现较多的症状为:疲乏、面色异常、口味异常、健忘、腰酸、腰膝无力、食欲不振和不寐(>50%),出现较多的舌脉象为:白苔,淡白舌和细脉。面色异常、腰酸头晕、心悸、气短、面色萎黄、神志异常、特殊汗出、耳鸣、手足不温、自汗、白苔、齿痕舌、薄苔和弱脉在贫血组中出现频率较高脂血症组高(P<0.05);腰膝无力、食欲不振、腹胀荣润舌、厚苔、腻苔和滑脉在高脂血症组出现较贫血组高(P<0.05)。结论:艾滋病患者经HAART治疗后并发贫血和高脂血症的证候以虚为主,主要涉及脾、心、肝、肾。贫血患者出现证型最多的是气血两虚证,其次是脾肾亏虚证,肝肾亏虚证。高脂血症患者出现证型最多为脾气亏虚,肾精亏虚,与脾、肾密切相关。

This study was aimed to analyze four diagnostic methods of AIDS patients with HAART complicated with anemia and hyperlipidemia.Characteristics of traditional Chinese medicine（TCM） and common pathogenesis were discussed in this article.This study was supported by Key Project of the National Eleventh-Five Year Research Program of China.This study was conducted through the retrospective analysis.This analysis was made on the four diagnostic methods of AIDS patients with HAART treatment.The results showed that the most frequent symptoms of AIDS patients with anemia or hyperlipidemia are fatigue,facial abnormalities,taste abnormalities,forgetfulness,backache,weakness of back,loss of appetite,insomnia.And the frequent tongue and pulse are white tough coating,pale tongue and fine pulse.The most frequent symptoms of the anemia group are facial abnormalities,backache,dizziness,palpitations,shortness of breath,pale complexion,abnormal state of mind,abnormal sweating,tinnitus,cold hands and feet,spontaneous sweating,white tongue coating,tooth-printed tongue,thin tongue coating and weak pulse（P ＆lt; 0.05）.The most frequent symptom of hyperlipidemia are lassitude,weakness,loss of appetite,abdominal distension,moisture tongue,thick and greasy tongue coating,slippery pulse.It was concluded that syndromes of AIDS patients on ARV complicated with anemia and hyperlipidemia are mainly deficient pattern,which affects the spleen,heart,liver and kidney.The most frequent syndrome type with anemia patients is blood deficiency,which is followed by spleen-kidney deficiency syndrome,liver-kidney deficiency syndrome.The most frequent syndrome type with hyperlipidemia patients is spleen qi deficiency and kidney essence deficiency,which are closely related to the spleen and kidney.