无症状脑梗死研究进展

Advances in silent brain infaltion

无症状脑梗死（silent brain infarction，SBI）主要靠颅脑影像学诊断，多见于老年人群，被认为是有症状脑梗死和认知损害的早期临床阶段。其危险因素包括年龄、吸烟史、高血压、糖尿病、代谢综合征、颈动脉粥样硬化、慢性。肾脏病、心房颤动和睡眠呼吸暂停等，相关血清生物学标记物包括高敏C-反应蛋白、同型半胱氨酸、血脂、尿酸、可溶性细胞间黏附分子-1。文章就SB!的影像学特征、危险因素、血清生物学标记物和临床意义进行了综述。

Silent brain infarction （SBI） is mainly diagnosed by brain imaging which is more common in the elderly population. It is considered as the early clinical stage of symptomatic cerebral infarction and cognitive impairment. Its risk factors include age, history of smoking, hypertension, diabetes, metabolic syndrome, carotid atherosclerosis, chronic kidney disease, atrial fibrillation, and obstructive sleep apnea. The related serum biological markers include high-sensitivity C reactive protein, homocysteine, cholesterol, uric acid, and soluble intercellular adhesion molecule-1. This article reviews the advances in research on the imaging characteristics, risk factors, serum biological markers and clinical sijmificance of SBI.