摘要
OBJECTIVE:To probe the toxicity and relative application theory of the commonly-used traditional Chinese herbal drug Taoren(Semen Persicae),and set up a correct attitude and principle and method to use Taoren(Semen Persicae) for treating the syndrome of stagnation of blood stasis and others in TCM clinic.METHODS:In this study,we analyzed and probed the ancient and modern literature research about Taoren(Semen Persicae),and summarized the realization of its toxicity and application contraindications in ancient herbals and the research assertion of its processing,drug-nature,pharmacologic actions,adverse reaction,and clinical reasonable application in modern literature.RESULTS:We found that some TCM doctors were worried about the effect of Taoren(Semen Persicae) 's disintegrating blood stasis to impair body's healthy Qi and its toxicity,and were not good at using this herb.And some patients were afraid of its toxic and side-effect not to take it.In the ancient and modern literatures some proper hates of Taoren(Semen Persicae) existed,and the toxicity component was also clear-cut,and the applications of Taoren(Semen Persicae) were in many fields especially the gynecological and traumatological diseases.The key root of toxicity generation and unreasonable application of Taoren(Semen Persicae) lies in taking without syndrome differentiation or using with overdosage.CONCLUSION:Under the precondition of correct processing,treatment based on syndrome differentiation,and taking the dosage stipulated by laws to apply Taoren(Semen Persicae) should be quite safe.The ancient and modern literature records and researches about Taoren(Semen Persicae) provide the determinate reference for understanding Taoren(Semen Persicae)'s efficacy and drug-nature(toxicity) more objectively and also for further correctly clinic recognition and research on Taoren(Semen Persicae).
OBJECTIVE： To probe the toxicity and relative appli- cation theory of the commonly-used traditional Chinese herbal drug Taoren （Semen Persicae）, and set up a correct attitude and principle and method to use Taoren （Semen Persicae） for treating the syn- drome of stagnation of blood stasis and others in TCM clinic. METHODS： In this study, we analyzed and probed the ancient and modern literature research about Taoren （Semen Persicae）, and summarized the real- ization of its toxicity and application contraindica- tions in ancient herbals and the research assertionof its processing, drug-nature, pharmacologic ac- tions, adverse reaction, and clinical reasonable ap- plication in modern literature. RESULTS： We found that some TCM doctors were worried about the effect of Taoren （Semen Persicae） ＇s disintegrating blood stasis to impair body＇s healthy Qi and its toxicity, and were not good at us- ing this herb. And some patients were afraid of its toxic and side-effect not to take it. In the ancient and modern literatures some proper hates of Tao- ren （Semen Persicae） existed, and the toxicity com- ponent was also clear-cut, and the applications of Taoren （Semen Persicae） were in many fields espe- cially the gynecological and traumatological diseas- es. The key root of toxicity generation and unrea- sonable application of Taoren （Semen Persicae） lies in taking without syndrome differentiation or using with overdosage. CONCLUSION： Under the precondition of correct processing, treatment based on syndrome differen- tiation, and taking the dosage stipulated by laws to apply Taoren （Semen Persicae） should be quite safe. The ancient and modern literature records and re- searches about Taoren （Semen Persicae） provide the determinate reference for understanding Taoren （Semen Persicae）＇s efficacy and drug-nature （toxici- ty） more objectively and also for further correctly clinic recognition and research on Taoren （Semen Persicae）.
基金
Supported by the National Natural Science Foundation of China (No. 81202659)
Scientific Research Start Foundation for New Teacher of Xiamen University (ZK1014)
Building Project of English Curriculum-Chinese Materia Medica of Xiamen University (X13200)
关键词
合理应用
桃仁
毒性
文学
古代
临床
基础
CAE
Semen Persicae
Drug toxicity
Pharma-cologic actions
Blood stasis
