经后路一期病灶清除、自体植骨融合、内固定治疗胸腰椎结核疗效观察

Effects of Posterior Anterior Radical Debridement,Bone Graft Fusion,Internal Fixation on Treating Thoracic and Lumbar Tuberculosis

目的:研究经后路一期病灶清除、自体植骨融合、内固定治疗胸腰椎结核的疗效。方法:选择胸腰椎结核的患者作为研究对象,随机分为给予自体植骨融合的观察组和椎间融合器植骨融合的对照组,观察手术相关指标、椎体功能相关指标、活动状态和生活质量。结果:观察组手术时间、术中出血量、术后引流量、术后卧床时间、Cobb角均明显少于对照组;治疗后椎间隙高度、椎体融合率、KPS评分和生活质量优良率明显高于对照组。结论:经后路一期病灶清除、自体植骨融合、内固定治疗能够改善治疗效果、提高生活质量,具有积极的临床价值。

Objective： To study the effects of posterior debridment, autologous bone graft fusion, internal fixation on treating tuberculosis. Methods： Thoracic and lumbar tuberculosis patients were collected and randomly divided into the observation group given autologous bone fusion and the control group given intervertebral fusion device. Then, operation indexes, vertebral body function indica- tors, activity state and quality of life were observed. Results： Operation time, bleeding volume, postoperative drainage volume, lying time, Cobb angles in the observation group were significantly less than those in the control group; the height of intervertebral space, vertebral fusion rate, KPS score and life quality in the observation group were significantly higher than those in the control group. Conclusion： Pos- terior debridment, autologous bone graft fusion, internal fixation have positive clinical value for improving the curative effect and quality of life.