复方氯己定取代双氧水为气管插管患者行口腔护理的可行性研究

The Research about the Feasibility of the Chlorhexidine Solution of Compound to Replace the Hydrogen Peroxide Solution in the Oral Care to Patients with Orotracheal Intubation

目的:研究复方氯己定含漱液取代过氧化氢口腔护理液的可行性。方法:将我科2009年10月-2010年10月101名经口气管插管住院患者随机分成实验组和对照组两组,其中实验组51例患者采用复方氯己定含漱液为口腔护理液,对照组50例患者采用3%过氧化氢为口腔护理液,每天进行2次特殊口腔护理,连续3天,比较两组患者在口腔炎症、黏膜改变、口腔异味三项指标上的差异。结果:实验组与对照组在控制口腔感染、保护黏膜完整、治疗口腔异味各项比较中均没有显著性差异,P>0.05。结论:复方氯己定含漱液拥有与3%过氧化氢同样的效果,且使用中不会产生危害人体健康的大分子自由基,且刺激和过敏反应较少,是能够取代3%过氧化氢溶液为经口气管插管患者进行口腔护理的溶液。

Objective： The study on the feasibility of the chlorhexidine solution of compound to replace the hydrogen peroxide Solution. Methods： During from October 2009 to January 2011, the number of patients with orotracheal intubation is 101, Patients were randomly divided into the experimental group and the control group. The compound chlorhexidine gargle was used in the 51 patients in experimental group, while the 3% hydrogen peroxide gargle was used in the 50 patients in in the control group. 2 times per day for a spe- cial oral care continue 3 days. Results： There is no significant differences in the oral infections control, the oral mucosa protection and the bad breath treatment comparing between the experimental group and the control group, P〉0.05. Conclusion： The effect of the compound Chlorhexidine gargle is same as that of the 3% hydrogen peroxide gargle without causing harmful macromolecular radicals to human health, and has less stimulus or anaphylactic reaction. Thus, it is an oral nursing gargle which can replace the 3% hydrogen peroxide gar- gle for the patients with orotracheal intubation.