摘要
目的 观察颅脑外伤病人伤后血清甲状腺激素的变化。方法 17例急性颅脑外伤病人分为重症组( GCS≤ 8’)及轻症组 ( GCS>8’) ,用放射免疫法分别测定其伤后早期的血清甲状腺素水平。结果 在颅脑外伤后早期 ,两组病人的 FT3 均低于正常 ,以重症组明显 ;重症组的 FT4、TT3 及 TT4水平均低于轻症组 ,而且重症组病人中TT3 水平低于正常的病例数明显多于轻症组 ( P <0 .0 5 )。结论 早期颅脑外伤病人中 ,甲状腺激素水平均有不同程度的降低 。
Objective To study the alteration of serum thyroxine in acute head injury at early stage.Methods Seventeen cases of acute head injury were divided into two groups:slight group (10 cases,with GCS>8’) and severe group (7 cases,with GCS≤8’).Serum thyroxine was measured with RIA.Results Serum levels of FT3 in both groups were lower than the normal range, especially in severe group.Average serum levels of TT3,FT4 and TT4 in severe group were also lower than those in slight group (P<0.05;0.01;0.05 respectively).There were more cases with reduced serum thyroxine level in severe group than slight group.Conclusion The serum level of thyroxine is somewhat decreased at the early stage of acute head injury cases,especially in the severe cases.
