micro RNA在乳腺癌化疗耐药机制中的研究进展
摘要
乳腺癌是影响全球数百万女性的最常见的恶性肿瘤之一[1],目前治疗乳腺癌的主要方法是手术治疗同时进行辅助治疗;辅助治疗主要包括:细胞毒素抗癌药物治疗、激素治疗、靶向药物治疗,或者联合几种方法进行综合治疗。
出处
《现代中西医结合杂志》
CAS
2013年第20期2278-2280,共3页
Modern Journal of Integrated Traditional Chinese and Western Medicine
参考文献27
-
1Pogribny 1P, Filkowski JN,Tryndyak VP, et al. Alterations of mi- croRNAs and their targets are associated with acquired resistance of MCF - 7 breast cancer cells to cisplatin [ J ]. Int J Cancer,2010,127(8):1785 -1794.
-
2Zhao JJ, Lin J, Yang H,et al. MicroRNA - 221/222 negatively reg- ulates estrogen receptor alpha and is associated with tamoxifen re- sistance in breast cancer[ J]. J Biol Chem,2008,283(45):31079- 31086.
-
3Xin F, Li M, Balch C, et al. Computational analysis of microRNA profiles and their target genes suggests significant involvement in breast cancer antiestrogen resistance [ J ]. Bioinformatics, 2009,25 (4) :430 -434.
-
4Gottesman MM ,Ling V. The molecular basis of multidrug resistance in cancer: the early years of P-glycoprotein research [ J]. FEBS Lett 2006,580(4) :998 - 1009.
-
5Ingelman-Sundberg M, Rodriguez-Antona C. Pharmacogenetics of drug-metabolizing enzymes:implications for a safer and more effec- tive drug therapy[ J]. Philos Trans R Soc Lond B Biol Sci 2005, 360 ( 1460 ) : 1563 - 1570.
-
6杜丽敏,沈利军,王如美,李文静.Ezrin与Muc1异常表达与乳腺癌转移的关系[J].现代中西医结合杂志,2012,21(14):1490-1491. 被引量:1
-
7Zhao H,Shen J; Medico L,et al. A pilot study of circulating miR- NAs as potential biomarkers of early stage breast cancer[ J]. PLoS One,2010,5 (10) :e13735.
-
8Hiscox S, Morgan L,Barrow D ,et a[. ,Tamoxifen resistance in breast cancer cells is accompanied by an enhanced motile and invasive phenotype:inhibition by gefitinib ( ' lressa' , ZD1839 ) [ J ]. Clin Exp Metastasis ,2004,21 (3) :201 - 212.
-
9路延芹,赵光明,张雪鹏.ADAM17-siRNA对MCF-7人乳腺癌细胞增殖的影响[J].现代中西医结合杂志,2011,20(24):3003-3005. 被引量:9
-
10Nuyten DS, Kreike B, Hart AA, et al. Predicting a local recurrence after breast-conserving therapy by gene expression profiling [ J ]. Breast Cancer Res,2006,8 ( 5 ) : R62.
二级参考文献19
-
1张凯丽,李艳玉,王树峰,郑宝恒,底旺,郭淑云,蔡建辉.MUC1和CK7在乳腺癌外周血微转移检测中的应用[J].中国肿瘤临床,2006,33(6):329-331. 被引量:10
-
2江忠清,连成瑛,郑秀.Ezrin分子生物学特性及其与妇科恶性肿瘤关系的研究进展[J].中华肿瘤防治杂志,2007,14(11):868-871. 被引量:13
-
3Garton KJ, Cough PJ, Blobel CP,et al. Tumor necrosis factor-alpha- convening enzyme ADAM17) mediates the cleavage and shedding of fractalkine ( CX3CL1 ) [ J ]. J Biol Chem, 2001,276 (41) : 37993 - 38001.
-
4Black RA,Rauch CT, Kozlosky CJ,et al. A metalloproteinase disin- tegrin that releases tumour-necrosis factor-alpha from cells[ J']. Na- ture, 1997,385 (6618) :729 - 733.
-
5Gschwind A, Hart S,Fischer OM, et al. TACE cleavage of proam-phiregulin regulates GPCR-induced proliferation and motility of cancer cells[J]. Embo J,2003,22(10) :2411 -2421.
-
6Wheeler DL,Ness KJ, Oberley TD,et al. Protein kinase Cepsilon is linked to 12 - O - tetradecanoylphorbol - 13 - acetate-induced tumor necr-osis factor-alpha ectod-omain shedding and the develop- ment of meta-static squamous cell carcinoma in protein kinase Ceps- ilon transgenic mice[ J ]. Cancer Res,2003 ,63 :6547 - 6555.
-
7Zheng X, Jiang F, Katakowski M,et al. Sensitization of cerebral tis- sue in nude mice with photodynamic therapy induces ADAM17/TA- CE and promotes glioma cell invasion [ J ]. Cancer Lett, 2008,265 (2) :177 -187.
-
8Zheng X, Jiang F, Katakowski M, et al. Inhibition of ADAM17 re- duces hypoxia-induced brain tumor cell invasiveness [ J]. Cancer Sci,2007,98 ( 5 ) : 674 - 684.
-
9Stemlicht MD,Sunnarborg SW. The ADAMI7 - amphiregulin - EG- FR axis in mammary development and cancer [ J ]. J Mammary Gland Biol Neoplasia,2008,13(2) :181 -94.
-
10Lamb RF, Roy C, Diefenbach TJ, et al. The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GT- Pase Rho [ J ]. Nat Cell Biol,2000,2 ( 5 ) :281 - 287.
共引文献8
-
1张艳,张雪鹏,吕捷,杨艳君.ADAM17在脑胶质瘤中表达的研究[J].肿瘤学杂志,2013,19(4):307-308. 被引量:7
-
2丁华,张雪鹏.ADAM17与肿瘤关系的研究进展[J].临床合理用药杂志,2014,7(26):178-179. 被引量:2
-
3丁华,孙影,张雪鹏,赵霞,胡宝山.转染ADAM17-shRNA的大鼠骨髓间充质干细胞对MCF-7人乳腺癌细胞侵袭能力的影响[J].广东医学,2014,35(14):2154-2156. 被引量:8
-
4彭晓兵,孙影,张雪鹏,张艳,吴春涛,胡宝山.转染ADAM17-shRNA的骨髓间充质干细胞对MCF-7乳腺癌细胞增殖能力的影响[J].广东医学,2015,36(19):2955-2958. 被引量:8
-
5陈国福,吴丽君,张雪鹏,蔡准,孟祥潮.缺氧条件下沉默解聚素-金属蛋白酶17基因对人乳腺癌MCF-7细胞增殖的影响[J].中国现代医学杂志,2016,26(15):22-27. 被引量:5
-
6张艳,胡宝山,杨慧敏,孙影,张雪鹏.ADAM17和Notch1在浸润性乳腺癌组织中的表达及意义[J].山东医药,2016,56(32):71-73. 被引量:4
-
7张笑博,彭晓兵,张雪鹏,孙影,贾文婷.沉默ADAM17基因对裸小鼠MCF-7乳腺癌移植瘤的影响[J].广东医学,2018,39(2):187-191. 被引量:2
-
8葛志鹏,张博,王晓涛,黄志强,张琪,田炜,张国志.沉默ADAM17基因对人甲状腺乳头状癌细胞增殖、迁移及侵袭的影响[J].山东医药,2018,58(10):9-12. 被引量:3
-
1王诚一.这几种方法可使人长寿[J].求医问药,2009(4):49-49.
-
2陈大坤.几种方法治疗子宫内膜癌的疗效分析[J].四川医学,2003,24(1):30-31.
-
3沈镇宙.治疗乳腺癌的几种方法[J].抗癌,1998(1):16-17.
-
4朱妍.兔VX_2肝癌模型的建立的综述[J].当代医学,2010,16(1):31-33. 被引量:2
-
5曹慧娟,王文玉,孙淑军,戴建业,毛文伟,张永煜.肺癌基因治疗的方法[J].中华中医药学刊,2012,30(6):1354-1356.
-
6杨海涛.关于分化型甲状腺癌治疗现状及进展研究[J].医学与社会,2015,28(B06):104-104.
-
7潘静.改善血清前列腺特异性抗原对前列腺癌诊断特异性的几种方法[J].国外医学(临床生物化学与检验学分册),2002,23(1):36-37. 被引量:3
-
8张怡,张倩,梁悦.妇科肿瘤中宫颈癌高危因素及筛查研究进展[J].首都食品与医药,2016,23(24):24-26. 被引量:3
-
9张元生.肿瘤不是不治之症[J].人人健康,2005,0(6):40-40.
-
10蒋永芳.肝癌基因治疗现状与展望[J].国外医学(流行病学.传染病学分册),2002,29(3):140-143.