儿童喘息性疾病患儿血微量元素 体液免疫及补体水平的变化

Changes of trace elements levels,immunity of body fluid and the complement level in children's asthmatic disease

目的分析儿童喘息性疾病患儿血微量元素及体液免疫的变化。方法选择64例喘息性疾病患儿为观察组,同时随机抽取来院体检的同年龄段的正常健康儿童56例作为对照组,对两组儿童进行血清中锌、铁、钙、镁的含量检测。结果观察组患儿Zn、Ca含量明显低于对照组儿童,差异有统计学意义(P<0.05);两组间Fe、Mg含量比较,差异无统计学意义(P>0.05)。患儿血清补体C4水平高于健康组,而IgG水平降低,差异有统计学意义(P<0.05)。结论儿童喘息性疾病与微量元素的缺乏及体液免疫、补体水平的改变密切相关,定期测量微量元素,及时纠正体液免疫及补体水平的紊乱,这对减少儿童喘息性疾病的发生有着重要意义。

Objective To analyze the changes of microelements levels and immunity of body fluid in children＇s asthmatic disease.Methods Sixty-four cases of repeated upper respiratory tract infection（children） were selected as an observation group,meantime a sampling 56 normal healthy cases（children） were randomized as a control group.The blood contents of zinc,iron,calcium,magnesium for both groups were analyzed.Results Observation group： zinc and calcium are lower than contrast group obviously.（P0.05）.There were not significantly different between the two groups in levels of iron and magnesium（P0.05）.The serum C4 level than the healthy group,but IgG level decreased,the difference was statistically significant（P0.05）.Conclusion Children＇ s Asthmatic Disease are related contents of trace elements,the complement level and immunity of body fluid in their body.It is very impartment for reducing children＇ s asthmatic disease to check trace elements and correct balance of immunity of body fluid and the complement level in children body.