复发性脑梗死TOAST卒中分型危险因素的分析

Analysis of recurrent stroke risk factors in different stroke subtype

目的探讨脑梗死复发的相关危险因素及与缺血性卒中分型的关系。方法回顾分析544例脑梗死患者的危险因素,比较复发与初发脑梗死两组患者不同TOAST分型中危险因素的差异。结果 544例脑梗死患者中,复发性脑梗死264例。在TOAST分型中,复发组最多亚型的患者是大动脉粥样硬化,此分型患者高血压病、糖尿病、脂代谢紊乱等危险因素要显著高于初发患者。结论高血压病、糖尿病、脂代谢紊乱等危险因素容易导致大动脉粥样硬化型卒中复发。

Objective To estimate the risk factors of recurrent cerebral infarction, and the distribution in different TOAST subtypes. Methods The risk factors of all ischemic stroke patients were analyzed retrospectively. All patients were classified as TOAST. The risk fac- tors between RCI（ recurrent cerebral infarction） and FCI（ first -ever cerebral infarction） were evaluated among the four types of stroke pa- tients. Results In our study, there were 264 patients of RCI and 280 patients of FCI. The rates of hypertension, diabetes, atrial fibrilla- tion, dyslipidemia and hyperhomocysteinaemia were higher in RCI than in FCI. In the research of TOAST subtypes, large - artery atheroscle- rosis （LAA） was the most common subtype among RCI patients. In the subtype of LAA, the rates of hypertension, diabetes, dyslipidemia and hyperhomocysteinaemia were higher in RCI than in FCI. Conclusion The advanced age, hypertension, diabetes, atrial fibrillation, d ys- lipidemia and hyperhomocysteinaemia are the most important risk factors for the recurrence of ischemic stroke.