颅内动脉瘤破裂出血介入治疗后早期持续腰大池引流对脑血管痉挛的影响

Influence of early continuous lumbar drainage on cerebral vasospasm after interventional treatment of intracranial aneurysm rupture hemorrhage

目的观察早期持续腰大池引流对颅内动脉瘤破裂出血介入治疗后脑血管痉挛(CVS)的影响。方法对89例Hunt-HessⅢ级颅内动脉瘤破裂出血患者进行介入栓塞治疗,术后患者随机分组,观察组给予早期持续腰大池引流,对照组给予间断腰穿释放脑脊液。观察两组患者并发症情况以及脑脊液红细胞以及压力等指标。结果观察组患者并发症明显低于对照组,CVS发生率低,且治疗后脑脊液红细胞以及压力明显较对照组下降(P<0.01)。结论早期持续腰大池引流能有效降低颅内动脉瘤破裂出血介入治疗后CVS的发生率。

Objective To observe the influence of early continuous lumbar drainage on cerebral vasospasm （CVS） after intcrventional treatment of intracranial aneurysm rapture hemorrhage. Methods Eighty-nine patients with Hunt-Hess III level of intracranial aneurysm rupture hemorrhage were given embolization treatment. The postop- erative patients were randomly divided into two groups： the observation group were given early continuous lumbar drainage, while the control group were given continuous lumbar puncture cerebrospinal fluid release. The index of complications, red blood cells and cerebrospinal fluid pressure of two groups, were observed. Results Compared with the control group, the observation group had significantly lower incidence of complications, lower incidence of CVS, reduced levels of cerebrospinal fluid red blood cells and decreased pressure （P〈0.01）. Conclusion Early con- tinuous lumbar drainage can effectively reduce the incidence of CVS after interventional treatment of intracranial an- eurysm rupture hemorrhage.