铜陵地区2845例孕妇TORCH感染状况分析

Analysis of 2 845 cases of pregnant women in Tongling area TORCH infection status

目的了解铜陵地区孕妇TORCH感染状况,分析其与妊娠年龄的关系。方法对2010年1月至2012年11月进行孕检的2 845例孕妇抽取血样,用酶联免疫吸附法对TORCH-IgM抗体进行检测。结果孕妇TORCH-IgM总阳性率2.601%,弓形虫(TOX),风疹病毒(RV),巨细胞病毒(CMV)和单纯疱疹病毒(HSVⅡ)IgM抗体阳性率分别为0.141%,0.211%,1.617%,0.738%;其中高龄(35～50岁)孕妇组TORCH-IgM总阳性率和CMV-IgM阳性率(6.178%,5.405%)均明显高于适龄(20～34岁)组(2.243%,1.237%)(P<0.01)。结论铜陵地区孕妇TORCH-IgM阳性率较低,高龄是孕妇发生CMV感染的一个高危因素,应加强孕妇的产前筛查,提高人口质量。

Objective To investigate TORCH infections among the pregnant women in Tongling city and analyze the relevance of gestational age with TORCH infections. Methods From January 2010 to November 2012,preg nant examination in 2 845 cases of pregnant women extracted from blood samples,testing for TORCH-IgM antibody by enzyme-linked immunosorbent assay in the hospital. Results The total positive rate of pregnant women TORCH- IgM was 2. 601%, toxoptasma （TOX）,rubella virus （RV）,cytomegalovirus （CMV） and herpes simplex virus （HSV Ⅱ） IgM antibody positive rate were 0. 141%,0. 211%,1. 617%,0. 738% respectively; the total positive rate of TORCH-IgM and the positive rate of CMV-IgM in women of advanced maternal age group （35- 50 years old） （6. 178%,5. 405%） were significantly higher than those in women of maternal age group （20-34 years old） （2. 243 %, 1. 237 % ）（P〈0.01）. Conclusion The positive rate of TORCH-IgM in pregnant women in Tongling area is relatively low,old age is a risk factor of CMV infection in pregnant women, should strengthen prenatal screening of pregnant women, improve the quality of the population.