多支血管病变PCI术后相关危险因素及其对预后的影响

Risk factors of multivessel disease(MVD) after PCI and their effect on prognosis

目的分析影响冠心病多支血管病变(MVD)患者经皮冠状动脉介入术(PCI)的危险因素及其对预后的影响。方法回顾性分析2005年12月至2010年12月该院行冠状动脉造影(CAG)明确为MVD病变并行PCI患者300例的临床资料,采用多因素Logistic回归分析影响其预后的危险因素。结果影响MVD患者PCI术后死亡的独立危险因素为:左室射血分数P=0.044,OR(95%CI)为2.617(1.025,6.679)、心力衰竭P=0.006,OR(95%CI)为4.379(1.529,12.538)、血管病变支数P=0.038,OR(95%CI)为2.663(1.055,6.723)及血运重建方式P=0.011,OR(95%CI)为0.431(0.226,0.821)。结论影响冠心病MVD患者PCI术后预后的独立危险因素为:EF、心力衰竭和血运重建方式;其中血运重建方式为影响预后最重要的独立危险因素。

Objective To investigate the risk factors of MVD patients with coronary heart disease after percutaneous coronary intervention（PCI） and their effect prognosis.Methods The clinical data of 300 MVD patients with coronary heart disease after PCI admitted from December 2005 to December 2010 were retrospectively analyzed based on coronary angiography（CAG）.Logistic multivariate regression analysis on models were used to find the independent risk factors.Results The independent risk factors for prognosis of MVD patients with coronary heart disease after PCI were left ventricular ejection fraction[P=0.044,OR（95%CI）=2.617（1.025,6.679）],heart failure[P=0.006,OR（95%CI）=4.379（1.529,12.538）],the number of vascular disease[P=0.038,OR（95%CI）=2.663（1.055,6.723）] and revascularization way[P=0.011,OR（95%CI）=0.431（0.226,0.821）].Conclusion Independent risk factors affecting the prognosis of MVD patients with coronary heart disease after PCI are EF,heart failure and revascularization way;And revascularization way is the most important independent risk factors to influence the prognosis of MVD patients with coronary heart disease after PCI.