中西医结合治疗动脉硬化闭塞症临床观察

Clinical observation on arteriosclerosis obliterans treated with combination of traditional Chinese and Western medicine

目的观察中西医结合治疗动脉硬化闭塞症(ASO)的临床疗效。方法将65例动脉硬化闭塞症患者(Ⅰ、Ⅱ期)分为治疗组32例,对照组33例。对照组以0.9%氯化钠10%mL加入凯时注射液10μg,静脉推注,1次/d,口服拜阿司匹林100mg,1次/d。治疗组在对照组的基础上内服自拟中药温经活血化痰汤治疗。两组均以30d为1个疗程,治疗1个疗程后观察疗效。结果治疗组总有效率为96.7%,疗效优于对照组的87.9%(P<0.05)。治疗组患者临床症状和体征及血液流变学有明显的改善,两组比较差异均有统计学意义(P<0.05)。结论中西医结合治疗动脉硬化闭塞症疗效显著,有改善下肢动脉血供的作用。

Objective To observe the clinical efficacy of arteriosclerosis obliterans（ASO） treated with combination of traditional Chinese and Western medicine. Methods 65 cases with ASO （Ⅰ, Ⅱ stage） were divided into the treatment group in 32 patients and the control group in 33 cases.The control group were treated with 10% mL 0.9% sodium chloride solution joined lOug Alprostadil injection by intravenous injection once daily,and oral Aspirin 100mg once daily.The treatment group were treated with oral self warming meridian,activating blood circulation and resolving phlegm Chinese herbal medicine decoction on the basis of the control group.30 days were a course of treatment for two groups,and the treatment effects after a course were observed. Results The total effective rate in the treatment group（96.7%） was better than that in the control group（87.9%）,（P 〈 0.05）.Compared with the control group,the clinical signs and symptoms and hemorheology in the treatment group improved significantly,the differences between two groups were significant（P 〈 0.05）. Conclusion Arteriosclerosis obliterans treated with combination of traditional Chinese and Western medicine has significant effect and improvement of artery of lower extremity.