血管内支架植入辅助弹簧圈栓塞与单纯开颅手术治疗颅内动脉瘤疗效对比观察

Comparative observation between the effect of endovascular stent implantation combined with guglielmi detachable coil embolization and simple craniotomy on intracranial aneurysm

目的研究血管内支架植入辅助弹簧圈栓塞治疗颅内动脉瘤的疗效。方法选择2009年3月～2012年3月我院收治的50例颅内动脉瘤患者进行回顾性分析。按照治疗方法不同将患者分为实验组和对照组。实验组采用血管内支架植入辅助弹簧圈栓塞对患者进行治疗,对照组采用单纯开颅手术对患者进行治疗。治疗后,采用格拉斯哥预后评分(GCS)标准,对两组患者治疗的临床疗效进行比较分析。结果本研究发现实验组患者治疗的良好率(68%)明显高于对照组(40%);实验组患者术后死亡率(0)明显低于对照组(16%),实验组患者的癫痫发生率8%)也明显低于对照组(32%),两组比较差异有统计学意义(P<0.05)。结论血管内支架植入辅助弹簧圈栓塞治疗颅内动脉瘤,疗效明显优于单纯开颅手术。

Objective To study the effect of endovascular stent implantation combined with guglielmi detachable coil embolization（ESIGDC） on intracranial aneurysm（IA）. Methods 50 cases of IA patients who were admitted into our hospital from Mar. 2009 to Mar. 2012 were selected as the subjects and divided into test group and control group according to their clinic time and treatment method. The test group was treated with ESIGDC,while the control group was treated with simple craniotomy. The GCS prognostic scoring standards were applied to comparatively analyze the clinical effect of two groups. Results In this study,the good rate of test group（68%） was obviously higher than control group（40%）. The mortality rate of test group（O）was obviously lower than control group（16%）,meanwhile,the epilepsy occurrence rate of test group（8%） was obviously lower than control group（32%）,there was a statistical significance between two groups（P 〈 0.05）. Conclusion The clinical effect of ESIGDC is obviously superior to simple craniotomy on IA therapy.