韵律加工脑机制的fMRI研究

Functional MRI study of prosodic processing

目的利用功能磁共振成像技术（fMRI），考察大脑在韵律加工中的作用，对韵律加工的神经机制进行探讨。方法应用3T磁共振成像系统与标准头线圈对13名在校大学生进行fMRI检查，年龄21～27岁，选择音高模式变化相似程度较高的成对材料，进行主动的音高模式的匹配判断，并采用AFNI软件进行分析。结果fMRI研究结果显示，除基本听觉区外，两侧大脑半球可见脑区激活，主要激活区域包括双侧颞上回、右侧额下回、辅助运动区和前运动区等脑区。结论颞上回与韵律加工密切相关，fMRI对理解韵律加工脑机制有重要作用。

Objective To explore the brain mechanism of prosody processing with functional magnetic resonance imaging （fMRI）. Methods In the current study, thirteen right-handed Chinese healthy volunteers （21-27 years） were performed to prosody tasks. The experimental materials were chosen similar pattern of pitch changes, fMRI data were acquired, then processed and functional areas of brain were localized in AFNI. Results fMRI demonstrated the activation of auditory regions. In addition, some brain regions of bilateral hemisphere were also shown activations. These brain regions included bilateral superior temporal gyrus, right inferior frontal gyrus, supplementary motor area, and premotor areas. Conclusion The superior temporal gyrus plays an important role in prosodic processing and fMRI is useful for understanding the cere- bral mechanism.