前列腺癌的病理误诊分析

Misdiagnosis analysis of prostatic carcinoma

目的探讨前列腺癌在石蜡切片中误诊情况,以总结经验,减少误诊的发生。方法收集近年来经过上级会诊或者科室最后病理确诊的前列腺癌存档蜡块和切片60例,对病理误诊情况进行分析。结果在60例前列腺癌患者中,有5例初诊误诊为前列腺增生(BHP)或者前列腺上皮内瘤变(PIN)或者非典型腺瘤样增生(AAH),误诊率8%。结论中低分化的前列腺癌不容易误诊,高分化的前列腺癌容易误诊为BHP、PIN或者AAH,此时加做免疫组织化学标记证实肌上皮细胞的存在是鉴别的关键。

Objective To investigate the misdiagnosis information of carcinoma of prostate in paraffin section, to summarize experience and decrease misdiagnosis. Methods To collect 60 cases of carcinoma of prostate paraffin block and section for the past few years, and carry out analysis of pathology misdiagnosis information. Results In carcinoma of prostate patient, 5 cases were misdiagnosised as hyperplasia of prostate or prostatic intraepithelial neoplasm of atypia adenomatoid hyperplasia, misdiagnosis rate was 8%. Conclusion The well-differentiated carcinoma of prostate easily is misdiagnosised as BHP、PIN or AAH, signed myoepithelial cell by immunohistochemistry technique was important to differentiate it.